2th

Question 1

Method of absorption for vitB12 and intrinsic factor

Answer 1

Endocytosis

Question 2

VitB12 and intrinsic factor absorption site

Answer 2

Terminal ileum

Question 3

Which is better at absorption solutions or suspensions

Answer 3

Solutions

Question 4

Sustained-release preparations absorption rate?

Answer 4

Slow in absorption

Question 5

Disintegration and dissolution rate for paracetamol and digoxin?

Answer 5

Rapid with paracetamol and slow with digoxin

Question 6

Quarternary ammonium Compounds ionization form

Answer 6

Always ionized (poor absorption)

Question 7

Tertiary amines (physostigmine)

Answer 7

Always unionized (better absorption)

Question 8

Aspirn is acidic or basic?

Answer 8

Acidic

Question 9

Amphetamine is acidic or basic?

Answer 9

Basic

Question 10

Streptomycin ionization and absorption

Answer 10

High pka»ionized&raquo_space;poor absorption

Question 11

Ion trapping aspirin cause what

Answer 11

Peptic ulceration

Question 12

Route of administration absorption rate

Answer 12

IV>inhalation >IM>SC>Oral>skin

Question 13

Absorbing surface vascularity absorption rate

Answer 13

Alveoli>skeletal muscles >subcutaneous

Question 14

Surface area absorption rate

Answer 14

Intestines >stomach

Question 15

What happens to absorption rate during diarrhea and malabsorption

Answer 15

Decrease in oral absorption

Question 16

What happens to absorption rate during shock and heart failure

Answer 16

Decrease in absorption

Question 17

Vit.B12 specific factor

Answer 17

Intrinsic factor

Question 18

Vit.C increase the absorption of what

Answer 18

Iron

Question 19

What does the activated charcoal do to oral absorption

Answer 19

Decrease oral absorption of most drugs

Question 20

Impact of SC adrenaline to absorption rate

Answer 20

VC»>decrease absorption rate of local anesthetics»longer action duration

Question 21

Transdermal drugs E.g

Answer 21

Nitroglycerin,estrogen

Question 22

Irritant drugs that mustn’t be taken on empty stomach

Answer 22

Aspirin

Question 23

What decrease the oral absorption of tetracycline

Answer 23

Milk(calcium)

Question 24

Gastric acidity (pH) increase the absorption of what drugs

Answer 24

Acidic drugs: aspirin barbiturates

Question 25

Intestinal alkalinity increase the absorption of what drugs

Answer 25

Basic drugs: amphetamines and ephedrine

Question 26

What drug accelerate gastric emptying

Answer 26

Metocloperamide»increase paracetamol absorption

Question 27

What drug slow down gastric emptying

Answer 27

Atropine»decrease paracetamol absorption

Question 28

Drugs metabolized in their hepatic first pass effect

Answer 28

Nitroglycerin & propranolol

Question 29

Gut 1st pass effect :Gastric acidity

Answer 29

Benzyl penicillin

Question 30

Gut 1st pass effect : digestive enzymes

Answer 30

Insulin & pituitary hormones

Question 31

Gut 1st pass effect :mucosal enzyme

Answer 31

L-dopa & alpha-methyldopa

Question 32

Gut 1st pass effect :mucosal enzymes

Answer 32

L-dopa & alpha-methyldopa