2nd test Flashcards

1
Q

What are the three different drug names

A
  1. chemical name
  2. approved name
  3. licensed, brand, trade or properietary name
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2
Q

What is the use of the chemical name on prescriptions?

A

Rarely used

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3
Q

What is the use of the approved name in prescriptions and give examples that describes what approved name is

A

it is used for prescribing official and prepared medicines

ex. British approved names (BAN)

United states approved names (USAN)

international non-proprietary names (rINN)

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4
Q

What is the use of licensed, brand, trade or proprietary name?

A

used for prescribing authorised medicines

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5
Q

Who gives the approved names?

A

Pharmacopoeia comission

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6
Q

Who gives the licensed, bran, trade or proprietary name?

A

manufacturers, can differ from the chemical name

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7
Q

Schedule 2 +3 drugs

How should it be written?

A

should be written indelible and the signature must be in ink or electronic

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8
Q

schedule 2 and 3 drugs

list 7 points of information that must be included in the prescription

A
  • Name and address of the owner
  • date on which the prescription was signes
  • name, form and strength of the preparation
  • total quantity of the number of dosage units in both words and figures
  • dose to be administered
  • prescriber’s signature, qualification and RCVS registration number
  • animal or herd under the vet’s care
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9
Q

Schdule 2+3 drugs

What are the rules concerning the signature

For how long is the prescription valid

and the rules about repeats

A

Signature: no latinisation or abbreviation

The prescription is valid for 28 days

Repeat presriptions are not permitted

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10
Q

What must the label include of dispensed veterinary medicines

A
  • name + address of the owner and veterinarian
  • date of dispensing
  • “for external use only” if only for topical use
  • the relecant withdrawal period
  • for what animals it should not be given too, due to drugs: aspirin
  • “for animal treatment only” unless the container or package is too small
  • “keep out of reach for children”
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11
Q

What is MFS?

A

medicated feeding stuff prescriptions

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12
Q

Who does the regulation of MFS apply to?

A

anyone who incorporates a medicated product of any description in an animal feeding stuff

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13
Q

Who does the MFS not affect?

A

companion animal owner administering a medical product mixed in the feed

or

farmer “top dressing” feed or medicating via the drinking water

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14
Q

What does the regulations (MFS) require from the manufacturers and distributors who adds medicines to feed?

A

it requires them to register with the royal pharmaceutical society of great britain (RPSGB)

or

the Department of Agriculture and Rural development for Northern Ireland (DARD for NI)

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15
Q

How many copies of MFS prescriptions are required?

A

Three copies

The compounder

the farmer

the veterinarian

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16
Q

How long is a MFS prescription valid?

A

3 months or shorter if indicated in the prescription

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17
Q

When and by who can medicines be incorporated into the feed?

A

by an appropriately registered person, if the product has a relevant product license or and animal test certificate

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18
Q

All the MFS should follow a specified format, what is needed?

A
  • the name and address of the person prescribing the product
  • the qualifications enabling the person to prescribe the product
  • the anem and address of the keeper of the animals to be treated
  • the species of animal, identification and muber of the animals
  • the premises at which the animal is kept if this is different from the address of the keeper
  • the date of the prescription
  • the signature or other authentication of the person prescribing the product
  • the name and amount of the product prescribed
  • the dosage and administration instructions
  • any necessary warnings
  • WP
  • the manufacturer or the distributor of the feedingstuffs
  • if the validity exceeds one month, a statement that not more than 31 days’ supply may be provided at any time
  • the name, type and quantity of feedingstuff to be used
  • the inclusion rate of the veterinary medicinal product and the resulting inclusion rate of the active substance
  • any special instructions
  • the percentage of the prescribed feedingsstuffs to be added to the daily ration
  • if it is prescribed under the cascade, a statement to that effect
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19
Q

What is meant when the dosage is divided?

A

the average of one dose is put into one unit (capsule)

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20
Q

What is meant when the dose is non-divided

A

one unit, the dosage is often a tablespoon or a handfull

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21
Q

What is needed in powders for external use?

A

the active substance: antibiotics, antiseptic

and

a binder: talcum, zinc oxide

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22
Q

What are the categories for powders for internal use?

A
  • water soulble powder
  • powder for in-feed use
  • powder for oral solution and suspension
  • for direct administration
23
Q

What is the composition of powders for internal use?

A

Active substance

binder: lactose, sorbit, glucose, bran flour, cereal flour, starch, rice

24
Q

What is meant by dividation?

A

divide in dose aequales No

less precise, quicker

25
Q

What is meant by dispensation

A

dentur tales doses No

more precise, slower

26
Q

What is the usage of granules?

A

Farm animals: mixed in feed or drinking water

Small animlas, human: for solution or mixed in feed

27
Q

What is the composition of granules?

A

active substance

Binder: saccharose, lactose

Adhesive: purified water, ethanol, methylcellulose

Coating: if needed

28
Q

What are the advantages of granules?

A

either the release can be quick, with fast decomposition

or/and

later release with a drug of another peak concentration, which will not decompose for hours after dosing

less frequent readministration

29
Q

What is a medicated premix used for?

A

it is used for preparing medicated feeding stuff

30
Q

What are some feed supplements?

A

microelements, vitamins, prebiotic

31
Q

What is the usage of premixes?

A

Per os: in small and large scale production

powder, granulated, liwuid

homogenous mixing

32
Q

What is the composition of premix?

A

Active substance

  • medicated premix: drugs (AB, antiparasitic aggents etc)
  • feed supplements: microelements, vitamins, prebiotics, probiotics

Binder

  • similar to feed
  • no nutritional value, cereal flour, wheat bran
  • indifferent: silicates
33
Q

What is the usage of capsules

A

pre os, without chewing

only for individual treatment

small animal medicine

34
Q

Soft capsule

A

Earlier: gelatine + sugar + glycerol + water

nowadays: synthetic polimers, thicker walls

35
Q

Hard capsule

A

Earlier: gelatine + sugar + water, dissolves in gastric fluid, approx 15 min disintegration

36
Q

Gastro-resistant capsule

A

soft + hard

film coated tablets

methacrylate coating

37
Q

What is the most precise divided form?

A

tablets

38
Q

how can tablets be administered?

A

Per os

intrauterine

intravaginal

for preparing solutions

39
Q

Composition of tablets

A

active substance

binder

adhesive

lubricant

coloring - flavouring agent

40
Q

Coating of tablets?

A

dragees, fim coated

for substances that irritates the stomach or dissolve there

TiO2 - protection from light

41
Q

Modified release tablets

A

insoluable matrix

  • single administration
  • chronic heart failure

soluble matrix

  • osmotically active pores in the tablet
  • OROS
42
Q
A
43
Q

What is intraruminal bolus and in which way are they releasing

A

large tablets given to ruminants

modified release

sustained release

pulse release

ex: ketosis or parasitic control

lasts for long period

44
Q

Packaging

A

usually plastic or aluminium foil and paper box

45
Q

What is the useage of herbal tea?

A

per os

topically: for washing wounds

46
Q

what is meant by infusion, herbal tea?

A

essential oils, substances that are easily dissolved

inactivation when expressed to permenent hot temperature

47
Q

What is meant by decoction?

A

sbstances that are difficult to extract - like tannic acid

48
Q

What is meant by maceration?

A

soaking

luke warm, 1 day to filtrate, heat sensitive substances

49
Q

What is the composition of herbal tea?

A

active substances with mild effect

herbal parts

ocasionally: effect enhancer chemiclas - potassium sodium tartrate for laxtaive herbal tea

50
Q

What is the usage of transdermal patches, implant?

A

continous, prolonged release

51
Q

What is the usage of transdermal patches?

A

drugs with excellent dermal absorption

systemic effects, such as analgesic

52
Q

What is the usage of subdermal implants?

A

frequently used

oestrus synchronisation

deslorelin: GnRH, chemically sterilize male, off label cat+ferrets, reversible: gets back the male function

53
Q

Collars and eartags as medicine?

A

antiparasitic, prescription is usually not required

54
Q

Vaginal delivery systems usage, pros and cons

A

oestrus synchronisation

horses dont tolerate it

might fall out