2nd line of defence Flashcards
1
Q
2nd line of defence
A
Internal non-specific
2
Q
Phagocytes (including macrophages + neutrophils) WHITE BLOOD CELLS
A
- WHITE BLOOD CELLS
- engulf + digest microorganisms + cell debris
- attracted to the scene by inflammatory response
3
Q
Phagocytes (including macrophages + neutrophils)
A
- white blood cells that engulf + digest microorganisms + cell debris
- attracted to the site by inflammatory response
4
Q
Inflammation is…
A
-a response to any damage in the tissue
5
Q
The purpose of inflammation is…
A
- reduce spread of pathogens
- destroy +prevent entry of additional pathogens
- begin the repair of damaged tissue
6
Q
4 signs of inflammation
A
- redness
- swelling
- heat
- pain
7
Q
Process of Inflammatory Response
A
- Tissue damage carries bacteria into wound
- Wounded cells release chemicals (chemokines) that stimulate mast cells
- Mast cells release histamine
- Histamine increases capillary blood flow + permeability
- Phagocytes leave capillaries + ingest bacteria + dead cells
8
Q
Fever is caused by…
A
the body’s pyrogens signalling the hypothalamus
9
Q
Fever is a defence mechanism….
A
that can destroy many types of microbes
10
Q
Fever helps fight….
A
viral infections
by increasing interferon production
11
Q
Innate: White blood cells
A
Leukocytes
12
Q
Neutrophils
A
Most common + ingest up to 5-20 bacteria
13
Q
Eosinophils
A
- allergic reactions
- can attack multicellular parasites
14
Q
Basophils
A
- allergic reactions
- can trigger histamine to trigger inflammation
- and heparin to prevent blood clotting
15
Q
Dendritic cells
A
antigen-presenting cells
