2B Flashcards
nucleic acids
organic biomolecules madeof repeating nucleotides that that store and transmit genetic information, thereby providing instructions protein sythensis.
2 types of nucleic acids
DNA(deoxyribose nucleic acid)
RNA(ribonucleic acid)
What are nucleotides made of up
phsophate group(PO4^3-)
5’ carbon attached is phosphate
3’ end connects the pentose sugar to the phosphate group of the other nucleotide.
1’ carbon is the nitrogenous base
where is dna found and how is it packaegedDNA
found in the nucleus of eukaryyotes, in humans DNA is packaged into 46 chromsoems each contiang thousands of genes
genes function
segmentof dnacarry instructions for the production of proteins
DNA
doublestraanded nucleicac acid and contains the coded instructiosn needed for an organism to develop, reproduce and survive.
Structure of DNA
Two strands of mutiple nucleotides which run antiparelle(5’ to 3’ in one direction and 3’ to 5’ in the other)
double helix is formed when hydrogen bonds form between the complemenaty nitrogneous bases
3 based are read together and called in DNA
a triplet
RNA
single stranded nucleic acid contaiin a ribose sugarand functions to transfer genetic information
3 types of RNA
mRNA
tRNA
rRNA
mRNA-messengerRNA
mRNA is a long strand of RNA that copies a strand of the DNA and brings it to the ribosomes from the nucleus for translation.
in RNA what is a codon
3 bases are read togehter this is known as a codon
tRNA-transferRNA
tRNA contains an anticodon and delivers a specific amino acid to ribosomes during translation to fomr a polypeptide chian
What is tRNA made up of
tRNA is made up of 3 nucleotides known as an anticodon
rRNA-ribosomalRNA
serves as the main strcutural componet of ribosomes within the cell and has a role in recogisning mRNA
How does rRNA make a ribosome, answer as both a 1 mark question and as a mutile mark question
rRNA folds into small subunits
Compare DNA and RNA
1.DNA is double stranded and long whilst RNA is single stranded and short.
2.DNA contains deoxyribose sugar, whereas RNA contains ribose sugar, therefore RNA contains one extra oxygen than DNA
3.The nucleotide bases of DNA are adenine, thymine, cytosine and guanine, whilst the bases of RNA are adenine, uracil, cytosine and guanine.
4.The function of DNA is to store genetic information for the long term, whilst the function of RNA is to to transfer genetic information.
- 3 nucletoides in DNA is knwon as a triplet, whilst 3 nucloetides in RNA is known as a codon
Hydrogen bonds are weak, how are they broken
hydrogen bonds are broken with little heat or the enzyme, polymerase
why and how does polymerase break hydrogen bodns
hydrogen bonds are weak, therefore polyermase is easily able to brken the hydrogen bonds by releasing energy from the phopshidiester bond formation
3 nucloeitides in DNA is known as
a triplet
monomers of nucleic acids
nucleotides
carbon 1 is attached… carbon 5
carbon 1 is what attaches the 5 carbon sugar to the nitrogenous base
Carbon 5 is what attaches the 5 carbon pentose sugar to the phosphate group.
bond that joins nucleotides together
phosphodiester bond
RNA full form
ribonucleic acid
PYRIMIDINES
made of one carbon ring, thymine and cysotinor uracil and cytoisne
Purines
made of 2 carbon rings- adenine and guainine
what does tRNA, mRNA and rRna stand for
tRNA
double helix
structure ofdnaconsists of two strands of DNA twisted around one another and connected in the center by hydrogen bonding
what does it mean when DNA runs in an antiparallel direction
antiparelle means that one strand of the DNA is running from a 3’ to 5’ end direction and the other strand of the DNA is running from a 5’ to 3’ end direction.
2) ONE STRAND RUNS IN A 3’ TO 5’ DIRECTION AND THE OTHER STRANDS RUN IN A 5’ TO 3’ DIRECTION. WHAT IS THIS CALLED
DNA that runs in an antiparelle direction
complementary base pairing
adenine binds with thymine and cytosine binds with guanine in DNA.A
phosophdister bond vs hydrogen bond
phosphodiester bond is the bond between the nucleotides s, whilst hydrogen bond is the bond between the complemenatry nitrogneous bases.
different between DNA and chromomes
DNA is the genetic infomraiton itself, chromosomes packaged version of DNA, seen in threadlike strands.
histones
proteins in which the DNA wraps itself around to package DNA into structural units called nucleosomes
similarites between RNA nad DNA
both formed of monomers known as nucleotides.
define gene
segment of DNAthat contains the genetic information to make proteins
ribosomes
site of protein sythensis
promotor region
thebeginning of sequence of DNA(TATA box) to which RNA polymerase binds to
operator region
where the repressor protein binds whihc prevnts the RNA poylermase from moving down the DNA sequenceand transcribing the structural gene.
an additional form of transcriptional regulation
attentuation
A section of DNA before the trp structural genes (trpE, trpD, trpC, trpB and trpA) is called
leader region
bio chemical pathway of trp