2.7.5. Integration of Cartilage and Bone Healing

Question 1

Stages in Bone Healing

Answer 1

1) bleeding
2) inflammation
3) proliferation
4) repair and remodeling

Question 2

What makes up the primary (soft) callus?

Answer 2

type 1 collagen (initially woven bone)

Question 3

What changes to make the secondary (hard) callus?

Answer 3

mineralization; happens late in healing/remodeling

Question 4

Match the macro process to it’s micro process:

Soft callus, fracture line gets fuzzy (osteoid being laid down by osteoblasts): motion is murky

Answer 4

Micro process:
new osteocytes

Second stage of bone healing

Question 5

Match the macro process to it’s micro process:

Blood, Trauma, Clot, Fracture Line: fracture Line gets bigger (osteoclasts are working) and motion is bad for healing

Answer 5

Micro processes:
Clotting factors, Platelets, Neural signalling, Microtrauma
Inflammatory Cascade

first stage of bone healing

Question 6

Match the macro process to it’s micro process:

Hard callus, fracture site stronger: motion is good for healing

Answer 6

Micro processes:
Resorption, remodeling, age of patient, calcium metabolism

third stage of bone healing

Question 7

How is tendon/ligamentous healing different from bone healing?

Answer 7

No blood vessels, therefore there isn’t release a bleeding phase and there in a limited inflammatory phase. Tendons do not heal like bones, albeit similarly