26 Feb 24 Flashcards

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1
Q

Common laxatives that give melanosis coli

A

Anthraquinone (senna) laxative abuse.

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2
Q

Normal crying span in infants

A

Intermittent consolable <3hr/day

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3
Q

What is Colic

A

🔹>-3hr/day (usually evening) , >-3days /week
🔹Healthy infant age <3months
🔹peaks at 6weeks
🔹resolves by age 3-4mo

Dx of exclusion

Ttt:
📣Reassure
📣Review soothing techniuqes; pacifier , holding rocking swaddling minimize external stimuli
📣Use swings , carriers , strollers
(To rest from active soothing)
📣Upright feeding (reduces aerophagia)

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4
Q

Causes of crying in Young infants

A

🔕Colic
🔕GERD :
▪️Freq spit up.
▪️Back arching after feeding

🔕Infection
AOM
Meningitis
Septic arthritis
UTI

🔕Intussusception
▪️Episodic irritability with legs drawn to abd
▪️Bilious emesis , bloodys tools

🔕Torsion

🔕Trauma
▪️Hair torniquet ; hair wrapped around digit
▪️Corneal abrasion : tearing , photophobia , fluorescein testing
▪️Abuse/ fracture : bruising, Laceration , asymmetric movements

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5
Q

Cyclic Vomiting Syndrome Etiology

A

📣Personal or Family History of Migraine

📣Episodes often have Identifiable trigger (infection, Stress)

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6
Q

Cyclic Vomiting Syndrome S/S

A

Stereotypical Vomiting episodes
🔹acute onset of Nausea , abd pain , headache , vomiting
🔹 self - limited , lasting 1-2days

Between Episodes
🔹 usually A/S
🔹 often Regular Intervals (2-4weeks)

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7
Q

Cyclical Vomiting Ttt

A

Abortive : Triptans

Supportives : Antiemetics , Rehydration

Most children have gradual resolution during adolescence.

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8
Q

What are the high risk features for foreign body ?

A

📣Pt has respiratory or Obstructive symptoms
📣Object is a button battery
📣Magnet
📣Sharp item

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9
Q

How to proceed with ingested Foreign Body

A

👁‍🗨PA / Lateral Xrays
(CT scan if object not visible on Xray)

👁‍🗨High risk features ➡️ do endoscopy

👁‍🗨. No high Risk features
⬇️
Serial Xrays (4-6hr)
↙️. ↘️
No transit : Object moving
Endoscopic removal Distally:
No intervention

👁‍🗨if S/S of abd pain / GI bleed develop or if magnets do not progress in the GIT , surgical removal is indicated.

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10
Q

Button battery ingestion

A

Button batteries create external current that leads to tissue Corrosion.
Leaking Alkaline battery solution causes Liquefactive Necrosis of surrounding mucosa.
Pressure Necrosis can also occur bcz of local inflammation and ischemia.

Prolonged impaction results in ulceration and perforation ,hemmorrhagic shock and death.
Fever , hematemesis and shock are signs of life threatening perforation.

Ttt: ▪️Emergency endoscopic removal
▪️Honey soon after ingestion in AS pts
▪️Delay increases risk for complications

     ▪️Barium Esophagography is done months after to see stricture formation in pts with severe injury.  (Avoid contrast in acute managemnet)
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11
Q

Fish Bone lodged in Esophagus.

A

Sharp objects (needles , pins , fish bone ) can lead to perforation and symptoms
Severe Acutely worsening Chest/abd pain
Vomiting with or w/o blood
Hemodynamic Instability.

Dx : Xray ( to see for signs organ perforation)
CT scan
Most fish bones are Radiolucent and seen only On CT.

🟤avoid induced emesis in case of FB aspiration , as it can cause esophageal damage and is not recommended.

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12
Q

Splenic Laceration dx and ttt

A

〰️dx: Follow table for BAT.

Ttt:
🟤Blunt splenic injury: Non operative management
Serial Hb measurement
Embolization

🟤Continuous hemodynamic Instability :
Do exploratory laporotomy.

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13
Q

Elderly with iron def and FOBT negative

A

Do colonoscopy and endoscopy

 A single negative FOBT is not sufficient to exclude occult GI bleed  Esp if no other obvious source of chronic blood loss is identified.
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14
Q

Lactation Failure Jaundice pathophys and CF

A

Age < 1 week
Insufficient intake of breast milk
⬇️ Bilirubin Elimination
⬆️ enterohepatic Circulation

CF :
Suboptimal BF
Signs of dehydration

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15
Q

Breast Milk Jaundice Pathophys and CF

A

Age > 1weeks (peaks at 2w)
⬆️beta Glucoronidase in breast milk
🔘 inc deconjugation of intestinal bilirubin
🔘 inc Enterohepatic circulation

CF :
▪️Adequate BF
▪️Well hydrated

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16
Q

Common Causes of Unconjugated Bilirubinemia in infants in first week

A

Physiologic Jaundice
Lactation failure jaundice

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17
Q

Lactation Failure Jaundice. ETIOLOGY

A

RF :
Exclusive BF
Ineffective latch

Mech:
Normally With freq breast feed (2-3hr) maternal milk production increases by Day 5.
Inadequate breast milk intake develops with infrequent feeding (every 4hrs) and delayed milk production (milk production increased around day 6).

The dec milk intake leads to delayed stooling (dec bilirubin elimination) and increased Enterohepatic Circulation of Unconjugated bilirubin.

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18
Q

Detailed CF of Lactation Failure jaundice.

A

📣First week of life
📣Jaundice (from UC bili) and signs of dehydration.
📣dec number of wet diapers.
📣 delayed transition from meconium to freq yellow stools )
📣 excessive weight loss >- 10% from birth weight

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19
Q

Ttt of lactation Failure jaindice

A

🔺BF every 2-3 hrs (improves bilirubin elimination)

🔺Monitor every 1-2 days.

🔺Continued signs of dehydration and rising bilirubin levels give Formula supplement and /or phototherapy

🔺 severe dehydration is ttt inpatient with IV fluids

20
Q

Retroperitoneal hematoma CF and Dx

A

Back pain
Use of Anticoagulants
Signs of hemodynamic compromise

Dx : do CT scan

21
Q

Atraumatic splenic Rupture. RF

A

⚫️Hematologic Cancers (Leukemia , lymphoma)
⚫️Infections (CMV , EBV , Malaria)
⚫️Inflammatory Dx (SLE, Pancreatitis)
⚫️Splenic Congestion. (Cirrhosis, Pregnancy)
⚫️Medications (anticoagulation, G-CSF)

22
Q

CF of Atraumatic Splenic Rupture

A

🟤Diffuse or LUQ abd pain , peritonitis
🟤Referred Lt shoulder pain (Kehr sign)
🟤Hemodynamic Instability

23
Q

Dx of splenic Rupture

A

➿Acute anemia
➿Intraperitoneal free fluid on imaging

24
Q

Ttt of splenic Rupture

A

🔺Catheter based Angioembolization
(Stable patients)

🔺Emergency splenectomy (unstable pts)

25
Q

Atraumatic splenic Rupture etiology

A

Splenic Capsule Stretches due to Infection or Malignancy.

Patients may have SS of fever , pharyngitis , LAD.

Splenic Rupture can occur even if spleen is not Palpable initially.

Activities that inc risk of Rupture (Contact sports) are avoided 3-4 weeks from the time of initial dx.

26
Q

Splenic Abscess RF

A

Recent abd surgery
(Complication as a result of distant infection- Infective Endocarditis , Cholecystitis)

HIV
Hematologic malignancy
DM

27
Q

CF of splenic abscess

A

🔻Fever
🔻Tender splenomegaly
🔻LUQ pain radiating to back (with or without splenomegaly)
🔻Anorexia
🔻Weight loss
🔻Leukocytosis with Leftward shift
🔻Elevated left hemidiaphragm(left pleural effusion)

28
Q

Dx of splenic abscess

A

CT scan of abdomen
AB
Splenectomy (many pts fail percutaneous aspiration due to occult microabscesses)

29
Q

Indications for Rotavaccine

A

Age 2-6Mo
(Live attenuated vaccine)

30
Q

Contraindications to Rotavaccine

A

🔶Allergy to vaccine ingredients

🔶SCID

🔶HO intussuception

31
Q

Shingles vs Postherpetic neuralgia

A

Shingles:
🔻Reactivation if VZV in DRG
🔻Pain (may precede rash)
🔻Vesicular rash in dermatomal dist
🔻Ttt: Antivirals

Post herpetic neuralgia :
🔺A complication if shingles
🔺Persistent hypersensitivity of afferent pain fibres leading to chronic pain
🔺Can be prevented by use of antivirals during shingles
🔺Ttt: Gabapantin

32
Q

Splenic Infarction RF

A

🔺Thrombosis due to Hypercoagulable state (cancer , SLE , Antiphospholipid antibody syndrome)

🔻Embolism due to Afib , endocarditis , atheroma

🔺Hemoglobinopathy (Sickle Cell dx)

33
Q

Splenic Infarction CF and Dx

A

CF:
Acute pain and tenderness in LUQ
Fever , Nausea
Splenomegaly
Leukocytosis
Signs of Lupus; longstanding joint pain , thrombocytopenia , young age

Dx : CT scan abd
ANA
Antiphospholipid AB
Echo(for vegetations)

34
Q

Polyarteritis Nodosa Pathophys

A

Segmental Transmural Inflmmation of medium sized arteries leading to luminal narrowing , thrombosis , organ ischemia.

🚺 corelation with underlying hepatitis B/C (immune complexes)

🚺 Fibrinoid Necrosis of arterial wall➡️luminal wall narrowing ➡️ tissue ischemia

🚺 Internal/External elastic Lamina damage ➡️ Microaneurysm Formation ➡️ Rupture and bleeding.

🎵luminal narrowing dec Blood flow and inc risk of thrombosis hence pts with PAN present with SS of Tissue Ischemia or infarction.

35
Q

CF of polyarteritis Nodosa

A

👁‍🗨Fever, Weight loss , Malaise
👁‍🗨SKIN : Nodules , Livedo Reticularis , Ulcers , purpura
👁‍🗨RENAL: Hypertension , Renal insuff , arterial aneurysms
👁‍🗨NERVOUS:
Headaches , seizures , mononeuritis multiplex
👁‍🗨GIT : mesenteric Ischemia/infarction
👁‍🗨MUSCULOSKELETAL. : myalgias, arthritis

36
Q

Dx of Polyarteritis Nodosa

A

🔴Negative ANCA and ANA

🔴Angiography: Microanuerysms and segmental/distal narrowing

🔴Tissue biopsy : nongranulomatous transmural inflammation

37
Q

Mesenteric Ischemia in Polyarteritis Nodosa

A

Signs of Mesenteric ischemia
Microaneuryms
Irregular aterial constrictions

Dx : mesenteric Angio

38
Q

Cystic Fibrosis Newborn screening

A

Newborn screening identifies only the most common CFTR mutations.
So consider CF in infants with
🔹Failure to thrive
🔹Recurrent Resp SS (freq coughing, cough with BL rhonchi)
Regardless of screening results.

Outcomes:
Steatorrhea
Vitamin Def ADEK
Poor weight gain

39
Q

Pt has A/S femoral hernia

A

Refer for elective Hernia repair ( due to risk for incarceration as contents pass thru narrow orifice)

Inguinal hernia have low risk for incarceration and strangulation as contents pass thru wide orifice.
Hence ressurance and watchful waiting is recomm.

40
Q

Post op abd wounds types

A

Superficial Wound Dehiscence:
▪️Separation of skin and subcut tissue with intact Rectus Fascia.
▪️Develop in first post op week
▪️Cause is Abnormal Subcut fluid buildup (seroma)
▪️Managed conservatively with careful dressing changes

Deep (fascial) wound dehiscence with evisceration;
🔕Non intact rectus fascia
🔕Exposure of intra abd organs to external env.
🔕1-2 weeks post op upto 30days.
🔕Emergency surgery due to risk of incerceration.

41
Q

Woman with inguinal bulge and signs if SBO

A

Femoral hernia

Incarceration occurs when hernia contents become trapped within hernia sac causing SBO.
Reduced venous outflow eventually leads to ischemia and necrosis (strangulation).

42
Q

Perforated Peptic Ulcer

A

Dx : Xray
(CT scan in case if Xray are negative and perforation is suspected)

Surgical consult
IV PPIs and BS antibiotics
Fluid resuscitation and NG suction
Emerigency surgery

43
Q

Epithelial Ovarian CA CF

A

🟤Acute :
SOB, obstipation/constipation with vomiting , abd distension

🟤Subacute:
Pelvic / Abd pain , Bloating , early staiety

A/S adenexal mass

🔺onset of constipation at an older age (age >- 50y) post menopausal esp accompanied by earky satiety or pain (sign of CA)

44
Q

Dx of epithelial ovarian CA

A

Inc Ca 125

USG:
Solid mass
Thick sepatations
Ascites

45
Q

Ttt of Epithelial ovarian CA

A

Exploratory Laporotomy