25.2. Mechanisms of Drug Interactions Flashcards
1
Q
Pharmaceutical /pharmacokinetic/pharmacodynamic interactions
A
- Diazapam
- Thiopentone
- Naloxone
- Propronolol
2
Q
Distribution and clearance
A
*Warfarin
*Phenytoin
*Aspirin
*Probenecid
*Methotrexate
Metoclopramide
Calcium
3
Q
Albumin/P450 inhibition/induction
A
*Warfarin
*Cimetidine
*Phenobarbitone
*Grapefruit juice
Isoniazid
Ketoconazole
4
Q
Acute and chronic differences
A
- Phenytoin
* Rifampicin
5
Q
Drugs with narrow therapeutic indexes
A
- Digoxin
- Warfarin
- Lithium