25. Rheumatic fever - etiology, pathogenesis, clinical presentation, evolution, treatment and prevention. Flashcards
1
Q
what is the aetiology of rheumatic fever
A
Rheumatic fever is an autoimmune reaction which occurs 2-3 weeks after a pharyngeal infection & can lead to a inflammatory reaction in heart, joints & skin
Beta-hemolytic group A streptococci
2
Q
what is the symptoms for rheumatic heart disease
A
dyspnea
nocturnal dyspnea - mitra valve stenosis
joints: assymetric polyarthritis of the large joints Skin: Subcutaneous rheumatic nodules Erythema anulare rheumaticum CNS: ▪ Chrorea minor
3
Q
diagnoses for rheumatic fever
A
Jones criteria: o Subcutaneous bleeding o Polyarthritis o Erythemaanulare o Chrorea o Carditis
Antibodies against metabolic products of A-streptococci
4
Q
what is the treatment for rheumatic heart disease
A
PenicillinV / amoxicillin
penicillin v - epigastric distress, diarrhea, constipation
cephalosprins 1st gen - cephalexin
oral thrush or a new yeast infection.
Treatment against inflammation o NSAIDS ibuprofen chronic ibuprofen use has been found correlated with risk of hypertension[24] and myocardial infarction (heart attack) dyspepsia,
Naproxen
heartburn,
ulcers and stomach bleeding