2.5 Biological Membranes Flashcards
What is the role of membranes at surface of cells?
- Partially permeable barrier between the cell and the environment- allows transfer of substances in and out of the cell.
- Site of chemical reactions
- Site of cell communication/signalling
What is the role of membranes within cells
- Compartmentalisation
-Controls what enters and leaves the organelle - Allows for concentration gradients to be established and maintained
- Embedding of enzymes into the membrane
Describe cell signalling
Communication between cells, cell recognition and identification, cells working together, to trigger a response
Describe the phospholipid bilayer
Hydrophilic phosphate heads orientate themselves towards water and hydrophobic fatty acid tails orientate themselves away from water (in extracellular fluid and cytoplasm)
Describe fluid mosaic
Fluid: components within the membrane move relative to each other (flexible)
Mosaic: embedded with proteins
Describe the function of glycolipids and glycoproteins
Cell recognition and identification
Cell signalling
Act as antigens
Act as receptors
Involved in cell adhesion
Describe the intrinsic proteins
Span the width of the membrane, usually transport proteins
Carrier proteins (transport large and polar substances), channel proteins (transport polar substances)
What is the role of cholesterol?
Found between the tails of the phospholipids in the bilayer and regulates membrane fluidity
How does temperature affect membrane fluidity?
As temperature increases the phospholipids gain kinetic energy
This causes gaps to appear between phospholipids
The membrane becomes more permeable
At high temperatures proteins in the membrane will denature
How does freezing affect membrane fluidity
When water freezes it expands and forms ice crystals which pierce and break the cell membrane
How do solvents (such as ethanol) and detergents affect fluidity?
Solvents and detergents dissolve the phospholipid bilayer increasing permeability
Define diffusion
The net movement of molecules from an area of high concentration to an area of lower concentration down a concentration gradient
Describe facilitated diffusion
Passive, requires a carrier/channel protein, molecules move down the concentration gradient
Describe active transport
Movement of substances against the concentration gradient using carrier proteins and ATP
Describe exocytosis
Cytoskeleton contracts to move a vesicle to the plasma membrane, the vesicle fuses with the plasma membrane releasing the contents