24. Properties of viruses Flashcards
enveloped viruses are disrupted by ___
acid
detergents
drying
heat
what are the morphological groups of viruses?
- naked icosahedral
- enveloped icosahedral
- naked helical
- enveloped helical
- complex
viruses are only visible under a __
electron microscope
how do you cultivate viruses?
living host cells
and enveloped virus is released by:
budding and cell lysis
cell lines
diploid, 50-70 passages
what happens to viral genomes of DNA viruses?
they remain in the infected cell, most reside in the nucleus (except pox viruses)
a naked capsid is stable to
- temperature
- acid
- proteases
- detergents
- drying
eclipse period
time from first infection to intracellular virus
almost all viruses contain either __ or __ with the exception of __
DNA, RNA, CMV
steps in viral replication
- recognition
- attachment and penetration
- uncoating
- macromolecular synthesis
- early mRNA codes for non-structural proteins
- late mRNA codes for structural proteins
- posttranslational modification of proteins
- assembly of viral components
- budding of enveloped viruses
- release of virus
can cells replicate RNA?
no, RNA viruses must encode an RNA-dependent RNA polymerase
most RNA viruses replicate in __
the cytoplasm
enveloped virus components:
membrane
lipids
proteins
glycoproteins
viruses that don’t use the cell polymerase __
carry their own polymerase