2.4 Cell Division Flashcards
What are the stages of the cell cycle in eukaryotic cells?
• Interphase
• Mitosis (PMAT)
• Cytokinesis
Interphase
• DNA replicates (S phase)
• Organelles replicate and cell grows (G1 and G2)
Prophase
• Chromosomes condense and become visible, appearing as 2 sister chromatids joined by a centromere
• Nuclear envelope breaks down
• Centrioles move to poles forming spindle
Metaphase
• Spindle fibres attach to chromosomes by their centromeres
• Chromosomes align along equator
Anaphase
• Spindle fibres contract
• Centromere divides
• Pulling chromatids to opposite poles
Telophase
• Chromosomes uncoil, becoming thinner
• Nuclear envelope reforms
• Spindle fibres break down
Cytokinesis
• Cytoplasm and cell membrane divides
• Forming 2 genetically identical diploid daughter cells
Why is mitosis important?
• Growth of multicellular organisms
• Replacing cells to repair damaged tissues
• Asexual reproduction
How can cancers form?
• Mutation in genes controlling mitosis
• Leading to uncontrollable cell division
• Resulting in a tumour / mass of abnormal cells
How do prokaryotic cells replicate?
• Binary fission
• Circular DNA replicates
• Plasmid(s) replicate
• Cytoplasm divides to produce 2 daughter cells
• One copy of circular DNA but variable number of plasmids