238 Neuro Flashcards
What is a myelography?
Test to see the subaranchnoid space, spinal cord, and vertebrae after injection of dye by LP
What is a contraindication to LP?
Increased ICP
What is specific of “neurogenic” or “central” DI?
It is caused by a lesion in the brain; it is the most common type
What is specific about “primary” DI?
It’s also called “psychogenic”, because it is caused by excessive water intake. Could be caused by a structural lesion in the thirst center or psych issues
What is “nephrogenic” DI?
It is when there is enough ADH in circulation, but decreased kidney response
What is one of the most common causes of Nephrogenic DI?
Lithium
How is central DI treated?
Desmopressin acetate is drug of choice; some form of vasopressin is used to replace missing ADH
How is Nephrogenic DI treated?
Low sodium diet and thiazide diuretics
What would be the clinical presentation of a patient with SIADH?
Hypobatremia; muscle cramping, weakness, dyspnea on exertion. As it get more severe: vomiting, abdominal cramps, muscle twitching and seizures
What is the treatment for SIADH?
Fluid restriction, duiretics (Lasix) and hypertonic saline.
What is Declomycin given for?
Treatment of SIADH; blocks the effects of ADH on the renal tubules (allowing a more dilute urine)
What is Samsca and Vaprisol given for?
They are vasopressin receptor antagonists (lessen the effect of AHD on the kidneys)
What disease results from a decrease in Acetylcholine-secreting neurons?
Alzheimer’s
What disease results from a reduction in acetylcholine receptors?
Myasthenia Gravis
What disease is due to destruction of dopamine-secreting neurons?
Parkinson’s
What does dopamine control?
Emotions, moods and regulation of motor control
What does Serotonin control?
Moods, emotions and sleep
What is normal ICP?
5-15
What is the brain’s use of glucose and oxygen?
20% of oxygen and 25% of glucose
What is normal CPP (cerebral perfusion pressure)?
60-100
What CPP indicates cerebral ischemia?
<50
What GCS score indicates a coma?
<8
What CSF lab value indicates infection?
> 5
The myelin sheath of CNS nerve fibers are composed of what?
Oligodendrocytes
The extrapyramidal carries impulses concerned with what?
Voluntary movement