23. Sleep-Disordered Breathing Flashcards

1
Q

what are the 3 neural stages?

A

wake, NREM, REM

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2
Q

sleep spindles and K complexes are characteristic of which stage of sleep?

A

stage 2

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3
Q

NREM is divided into 3 stages; what are they?

A

N1, N2, N3

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4
Q

what is stage N3 known as?

A

slow wave/deep sleep

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5
Q

REM is known as what?

A

Stage R

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6
Q

what occurs in REM

A

dreaming, skeletal muscles are paralyzed (to prevent acting out dreams), rapid eye movmeent

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7
Q

How long are typical REm cycles?

A

90 min. they grow longer in second half of the night.

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8
Q

main stimulus driving resp is what?

A

PC02

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9
Q

how is hypercapnia detected?

A

via medullary chemoreceptors as well as carotid body chemoreceptors

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10
Q

what occurs when we are in NREM sleep? what controls breathing?

A

no longer partly behavioral; purely metabolic.

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11
Q

what happens to the PC02 set point in sleep?

A

is is raised slightly, resultin gin mild hypoventilation.

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12
Q

what happens during REM with resp?

A

more reapid, more variable. may be due to behavioral inf related to dream content.

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13
Q

what happens with blood gas abnormalities during sleep?

A

they are made worse.

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14
Q

def of apnea?

A

complete cessation of airflow. can either be central or obstructive in origin.

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15
Q

what is OSA/what causes it?

A

obstructive sleep apnea/dynamic obstruction of upper airway, usually during inspiration.

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16
Q

what is the main stimulus for arousal with OSA?

A

likely the inc resp efforts

17
Q

treatment options: conservative

A

wt loss, avoiding EtOH, dental appliances.

18
Q

tx options: more severe

A

surgery, CPAP

19
Q

what is CSA?

A

central sleep apnea, due to decr in drive to breathe.

20
Q

what are most common types of CSA

A

cheyne-stokes (associated with congestive heart failure) and usu of opioid meds

21
Q

what are the cardiovascular consequences for a person with OSA?

A

sig higher risk for CV disease. more likely to dev systemic HTN, also stroke, ischemia, CHF. link is probably systemic inflammation (associated with both OSA and CHF).

22
Q

what is the connection between hypoxemia and pulm HTN?

A

hypoxemia is a vasoconstrictor in the pulm system!!! so lack of 02 can lead to pulm HTN.