2.3 Nucleotides and nucleic acids Flashcards

1
Q

DNA is a __________ which is a monomer?

A

Polynucleotide

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2
Q

What are the DNA nucleotides?

A

Cytosine (C)
Guanine (G)
Adenine (A)
Thymine (T)

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3
Q

What are complementary base pairs?

A

Cytosine with Guanine
Adenine with Thymine

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4
Q

Which two DNA nucleotides are purine?

A

Adenine and Guanine

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5
Q

Is purine double or single cyclic?

A

Double

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6
Q

Which two DNA nucleotides are pyrimidine?

A

Cytosine and Thymine

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7
Q

Is pyrimidine double or single cyclic?

A

Single

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8
Q

What is the sugar unit for DNA?

A

Deoxyribose

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9
Q

What else can a deoxyribose be called?

A

Pentose sugar

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10
Q

What is the bond between two nucleotides?

A

Phosphodiester bond

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11
Q

Where does the phosphodiester bond between two nucleotides happen?

A

Between the carbon 3 in the pentose sugar of one and the phosphate group of another.

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12
Q

Can the phosphodiester bond go between Adenine and Cytosine?

A

Yes, the hydrogen bonds have to bond complementary pairs.

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13
Q

What is the process called where DNA replicates itself?

A

Semi-Conservative replication.

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14
Q

What are the enzymes involved in semi-conservative replication of DNA?

A

Gyrase, DNA helicase, DNA polymerase, DNA ligase

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15
Q

What does ATP stand for?

A

Adenosine triphosphate

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16
Q

What is ATP?

A

Energy currency of the cell

17
Q

How much energy is released when one phosphate is removed from ATP?

18
Q

What reaction occurs in the breakdown of ATP?

A

Hydrolysis

19
Q

The breakdown or making of ATP is a _______ reaction?

A

Reversible

20
Q

Where does transcription happen?

A

The nucleus

21
Q

What nucleotide does RNA have instead of another?

A

Uracil instead of thymine

22
Q

What is the process of transcription?

A

DNA Helicase unwinds and unzips the relevant part of the DNA helix. (by breaking hydrogen bonds)
RNA polymerase attaches to the DNA.
One DNA strand acts as the template (sense strand), the other is redundant (antisense strand).
As RNA polymerase moves along the sense strand, ribonucleotides are assembled in a precise order due to complementary base pairing.
Fully formed mRNA (m stands for messenger) peels off the DNA and leaves the nucleus via a nuclear pore. The DNA then rewinds.

23
Q

Is mRNA single or double stranded?

24
Q

Where does the ribosome bond to the mRNA?

A

Start Codon

25
What does the mRNA move through (proteins)?
Large subunit and small subunit
26
What is the anticodon?
Triplet code of organic bases on tRNA
27
What is the codon?
Triplet code of organic bases on mRNA
28
What does the tRNA carry?
Amino acid
29
What allows the tRNA to bond with the codon?
Complimentary anticodon
30
The ribosome moves along the mRNA strand which causes what?
The tRNA to bind
31
What happens due to the amino acids being so close together?
Condensation reactions and the amino acids form a peptide bond
32
When the tRNA that carried the first amino acid is released, what is left behind?
Amino acid as a dipeptide
33
When is the polypeptide complete?
When the ribosome reaches the stop codon
34
When the polypeptide is released where does it go?
Golgi apparatus to be modified and packaged
35
If the mRNA isn't used again, what happens?
Broken down into nucleotides which can be assembled to produce a different polypeptide
36
What does universal mean (biologically)?
Found in all organisms
37
What does degenerate mean?
More than one codon for each amino acid
38
What is rRNA?
Ribosomal RNA catalyses the formation of a peptide bond between the two amino acids