2..3 Clinical: Edema

Question 1

Salt retaining drugs

Answer 1

NSAIDs
Fludrocortisone
Estrogens
Androgens

This can lead to generalized overfill

Question 2

Pregnancy and edema

Answer 2

Secondary renal Na+ H2O retention

Vasodilation–>Underfilling of EABV–>2nd Salt and water retention–>Increase cardiac OP–>Increase plasma and ECF vol

Question 3

Vasodilators

Answer 3

Underfill EABV–> Altered vol/capacitance ratio

Minoxidil
Diazoxide
Dihydropyridine calcium
channel blockers