2.2- DNA REPLICATION Flashcards
How are all cells formed?
cellular fusion
What is not formed by cellular fusion?
zygotes
How are all cells that make up a multicellular organisms derived and by what process?
derived from existing cells by process of division
In what two main stages does cell division occur?
nuclear division
cytokinesis
What is nuclear division?
process by which nucleus divides
what are the two types of nuclear division?
mitosis
meiosis
What is cytokinesis?
follows nuclear division and is process by which whole cell divides
What must happen before a nucleus divides?
its DNA must be replicated (copied)
Why must the DNA be replicated before the nucleus divides?
ensure that all the daughter cells have the same genetic information to produce enzymes + other proteins they need
What model of DNA replication is universally accepted?
semi-conservative model
What are the four requirements for semi-conservative replication to take place?
four types of nucleotide, each with their bases must be present
both strands of DNA molecule acts as template for attachment of nucleotides
enzyme DNA polymerase
source of chemical energy required to drive process
Process of semi-conservative replication #1
enzyme DNA helicase breaks hydrogen bonds linking base pairs of DNA
Process of semi-conservative replication #2
so double helix separates into its two strands + unwinds
Process of semi-conservative replication #3
each exposed polynucleotide stand then acts as a template to which complementary free nucleotides bind by specific base pairing
Process of semi-conservative replication #4
nucleotides joined together in condensation reaction by enzyme DNA polymerase to form “missing” polynucleotide strand on each of the two original polynucleotide strands of DNA