2.1.6 cell division, cell diversity and cellular organisation Flashcards
What are the three checkpoints in the cell cycle?
-G1 checkpoint
-G2 checkpoint
-Spindle fibre checkpoint
What is checked at the G1 checkpoint?
-cell size
-nutrients
-growth factors
-DNA damage
What is checked at the G2 checkpoint?
-cell size
-DNA replication
-DNA damage
What is checked at the Spindle fibre checkpoint?
-chromosome attachment to spindle
What happens at G0 in the cell cycle?
The cell leaves the cycle temporarily or permanently: for differentiation or DNA has become damaged and is not viable.
What happens at G1 in the cell cycle?
Cellular contents (apart from chromosomes) are duplicated, and protein synthesis and respiration occurs.
What happens at S stage in the cell cycle?
Each chromosome is duplicated.
What happens at G2 in the cell cycle?
Corrects any damage detected to the chromosomes, and cell increases in size.
The energy stores are also increased.
What happens in cytokinesis?
Cytoplasm is divided between the two daughter cells.
What happens in mitosis?
Nuclear division occurs-places one strand of each chromosome in each daughter nucleus.
Each nucleus is identical to parent nucleus.
What happens during Prophase in mitosis?
-Chromatin fibres condense to form chromosomes.
-Protein microtubules form spindle fibres linking to poles of the cell.
-Spindle fibres begin to move chromosomes to centre of the cell.
-Nuclear envelope disappears.
What happens during Metaphase in mitosis?
-Chromosomes are moved by the spindle fibres to form the metaphase plate.
What happens during Anaphase in mitosis?
-Centromeres divide: sister chromatids into daughter chromosomes.
-Cells elongate.
What happens during Telophase in mitosis?
-Nuclear envelope reforms.
-Chromosomes uncoil.
-Nucleolus reforms.
Why is mitosis important in life cycles?
-growth and tissue repair
-asexual reproduction
Why is meiosis important in life cycles?
-production of haploid cells
-genetic variation (by independent assortment)
What happens in Prophase 1 in meiosis 1?
-Chromosomes condense.
-Spindle formation begins.
-homologous chromosomes pair up-bivalents.
What happens in Metaphase 1 in meiosis 1?
-Bivalent pairs assemble along the metaphase plate.
-Independent assortment-paternal and maternal chromosomes can face either pole.
What happens in Anaphase 1 in meiosis 1?
-Homologous chromosomes pulled to opposite poles-chromatids stay joined.
-Sections of sister chromatids break off and re-join- exchange (genetic variation).