2.1.6: cell division Flashcards
what is the cell cycle?
a highly ordered sequence of events, resulting in the division of cells and the formation of 2 genetically identical daughter cells
what happens during the mitotic phase and the interphase?
- mitotic = mitosis
- interphase = g1, synthesis and g2
what happens at the growth one phase of the cell cycle?
proteins from which the organelles are synthesised are produced and organelles replicate. the cell increases in size
what happens during the synthesis phase of the cell cycle?
dna is replicated in the nucleus
what happens during the growth two phase of the cell cycle?
the cell continues to increase in size, energy stores are increased and the duplicated dna is checked for errors
what is the g0 phase?
given to the phase when the cell leaves the cycle either temporarily or permanently, due to damages cells and many sensecent cells that could cause damage/harm to the body
where is the g1 checkpoint and what does it check for?
- at the end of the g1 phase before entering synthesis
- cell size, nutrients, growth factors and dna damage
where is the g2 checkpoint and what does it check for?
- at the end of the growth two phase before the start of the mitotic phase
- checks for any errors in the dna and if it is the correct size
where is the metaphase checkpoint and what does it check?
- point in mitosis where all the chromosomes should be attached to the spindle and have aligned
- that the chromosomes are assembled correctly
what are the 4 stages of mitosis?
prophase, metaphase, anaphase and telophase
what happens during mitosis?
1) prophase - chromosomes condense and become visible in the nucleus. nucleolus disappears and the nuclear membrane begins to break down. a pair of centrioles move to either side of the cell. spindle fibres move chromosomes toward the centre of the cell
2) metaphase - spindle apparatus are completely formed and chromosomes are lined up in the centre
3) anaphase - centromeres divide into two and spindle fires begin to shorten. this pulls the sister chromatids towards the opposite poles
4) telophase - nuclear membrane reforms. chromosomes uncoil back to their chromatin state and the nucleolus reappears in each nucleus
what are homologous chromosomes?
chromosome pairs that are the same length, have the same centromere position and have the same genes
what are the 8 stages of meiosis?
prophase one, metaphase one, anaphase one, telophase one, prophase two, metaphase two, anaphase two, telophase two and cytokinesis
what happens during meiosis?
1) prophase 1 - chromosomes condense and thicken to become visible. homologous chromosomes pair up and crossing can occur (swapping genetic information)
2) metaphase 1 - homologous chromosomes line up on the equator of the spindle fibres (independent assortment of homologous chromosomes - pairs are randomly lined up at the equator)
3) anaphase 1 - spindle fibres contract and chromosome pairs are separated
4) telophase 1 - chromosomes arrive at the opposite poles of the cell to form 2 daughter cells
5) prophase 2 - chromosomes in each daughter cell prepare to migrate to spindle fibres
6) metaphase 2 - the chromosomes at each pole of the cell line up along the spindle fibres (chromatids are randomly moving)
7) anaphase 2 - spindle fibres contract and sister chromatids are pulled towards the opposite poles
8) telophase 2 - chromatids arrive at opposite poles to form 4 daughter cells
why does mitosis occur?
the development of embryos and replacing damaged cells