2.1.6 Cell Division Flashcards
1
Q
cell cycle
A
- interphase(G1, S and G2)
- nuclear division- mitosis or meiosis
- cytokinesis
2
Q
interphase
A
- Longest stage in the cell cycle
- When DNA replicates (S-phase) and organelles duplicate while cell grows (G1&G2-phase)
- DNA replicates and appears as two sister chromatids held by centromere
3
Q
mitosis
A
- One round of cell division
- Two diploid, genetically identical daughter cells
- Growth and repair (e.g. clonal expansion)
- Comprised of prophase, metaphase, anaphase and telophase(PMAT)
4
Q
prophase
A
- Chromosomes condense and become visible
- Nuclear envelope disintegrates
- In animals - centrioles separate & spindle fibre structure forms
5
Q
Metaphase
A
- Chromosomes align along equator of cell
- Spindle fibres released from poles now attach to centromere and chromatid
6
Q
Anaphase
A
- Spindle fibre contracts (using ATP) to pull chromatids, centromere first, towards opposite poles of cell
- Centromere divides in two
7
Q
Telophase
A
- Chromosomes at each pole become longer and thinner again
- spindle fibres disintegrate + nucleus reforms
8
Q
Cytokinesis
A
The division of the cytoplasm to create two new cells
9
Q
Mitotic index
A
- Used to determine proportion of cells undergoing mitosis
- Calculated as a percentage OR decimal
the number of cells in mitosis/ the total number of cells
x100 for percentage
10
Q
meiosis
A
Two nuclear divisions that result in four genetically different haploid daughter cells
11
Q
haploid
A
one copy of each chromosome
12
Q
diploid
A
two copies of each chromosome
13
Q
Genetic differences introduced by meiosis
A
- Independent assortment of homologous chromosomes
- Crossing over
mutationssss
14
Q
crossing over
A
- Chromosomes condense and thicken in prophase I
- Homologous chromosomes pair to form bivalents
- Crossing over can occur between the chromatids of bivalents
- This results in new combinations of alleles in the resulting gamete
15
Q
Independent assortment
A
- Homologous pairs of chromosomes line up opposite each other on either side of the equator during metaphase I
- It is random which side of the equator the maternal and paternal pair aligns
- As a result, each gamete receives a different combination of maternal and paternal chromosomes