2.1.5 - Biological Membranes Flashcards
What are the roles of a cell surface membrane?
- acts as a partially permeable barrier (between cell and environment)
- controls what enters/leaves the cell
- cell communication (cell signalling)
- allow recognition with other cells
- some chemical reactions
- sites of chemical reactions
What are the roles of a membrane within a cell?
- comparementisation (divides cell and keeps cell organelles separate)
- partially permeable barrier (between organelles and cytoplasm and within organelles)
- can form vesicles
- control what enters/leaves organelles
- sites of chemical reactions
What is cell signalling?
communication between cells
-one cell releases a molecule, which attaches to another cell’s receptor so that it is detected by the cell
What is the fluid mosaic model?
a model which shows the arrangement of molecules (eg. phospholipids, proteins, etc) in a cell membrane
What is the role of phospholipids within the fluid mosaic model of a cell membrane?
- acts as a barrier to large polar (dissolved) substances -water soluble substances can’t dissolve through as hydrophobic centre to bilayer don’t let them through
- fat soluble and small molecules can pass straight through
Describe the structure of phospholipids in the fluid mosaic model of a cell membrane
- form a bilayer
- hydrophilic phosphate heads on outside
- hydrophobic fatty acid chains on inside
- about 7nm thick
What is the role of cholesterol within the fluid mosaic model of a cell membrane?
- makes membrane less fluid and more rigid
- reduces permeability to charged particles
- interacts with phospholipids (hydrophobic end interacts with heads + hydrophilic ends interact with tails -pulls them together for stability)
What is the role of glycolipids within the fluid mosaic model of a cell membrane?
- act as antigens (cell markers)
- stabilise membrane by forming hydrogen bonds with surrounding water molecules
What is the role of glycoproteins within the fluid mosaic model of a cell membrane?
- stabilise membrane by forming hydrogen bonds with surrounding water molecules
- act as antigens (cell markers)
- act as receptors (for cell signalling)
What is the role of proteins within the fluid mosaic model of a cell membrane?
-control what enters/leaves cells
different types: channel proteins, carrier proteins, etc
What factors affect membrane structure and
permeability?
- temperature
- solvent
Why is it important that cell membranes are fluid?
- diffusion of substances across membrane
- fusing of membranes
- movement and shape change of cells
How does an increase of temperature affect the permeability of a membrane?
- increases permeability
- increased kinetic energy of phospholipids
- creates gaps between bilayer (disrupts it)
- molecules can pass through gaps
What is the structure and permeability of a membrane like below 0°C?
- phospholipids don’t have much energy so can’t move much (are packed closely together) so membrane is rigid
- channel and carrier proteins in membrane deform so permeability increases
What is the structure and permeability of a membrane like around 0-45°C?
- phospholipids can move and aren’t so packed together
- membrane is partially permeable
- as temp increases, permeability increases (more energy to move so more fluid)