2.1.5 Flashcards
What is the purpose of membranes?
- separate cell contents from environment
- separate organelles from each other and cytosol
What is meant by compartmentalisation?
Formation of separate membrane bound areas in cell
What is the purpose of compartmentalisation?
- Allows specific conditions for cellular reactions
- protects vital cell components
What is the plasma membrane made of?
Phospholipid bilayer
- hydrophilic phosphate heads on either side
- sandwiching the hydrophobic fatty acid tails
Why is it called fluid mosaic model?
- Phospholipids are free to move within layer relative to each other (making membrane fluid)
- different proteins are embedded (like mosaic tiles)
What are intrinsic proteins?
- Integral
- Have amino acid’s with hydrophobic our groups on external surfaces, so I kept in place as it interacts with hydrophobic cool.
Give four examples of intrinsic proteins
-Channel proteins
– carrier proteins
– glycoproteins
– glycolipids
What do channel proteins do?
Provide hydrophilic channel that allows passive movement of polar molecules and ions down conc. gradient through membrane
How are channel proteins held in place?
Hydrophobic R-groups that interact with hydrophobic core
What do carrier proteins do?
Passive and active transport (up a conc. gradient)
Involves protein changing shape
Where are glycoproteins found?
Embedded in membrane attached to carbohydrate (sugar) chains
What are the two uses of Glycoproteins?
- Cell adhesion
- receptors for chemical signals
How do you glycoproteins work as receptors for chemical signals?
-When a chemical binds to it it evokes a response from cell
-may cause direct response/set of series of events inside cell
Known as: cell signalling/cell communication
What do glycolipids do?
- Cell markers/antigens
- can be recognised by cells of the immune system As either self or non-self
What are extrinsic proteins?
Peripheral
Have a Hydrophilic R groups so interact with phospholipid heads or intrinsic proteins
Where are extrinsic proteins found?
In either layer or in between
What is cholesterol?
A lipid with a hydrophobic and hydrophilic end
What is the function of cholesterol and how does it do this?
-Regulates membrane fluidity
-add stability as it is in between the phospholipid tails of the bilayer limiting the amount that they can move
Prevents membrane from becoming too rigid by stopping phospholipid getting too close and crystallising