211 Test 1

Question 0

Leuk spreads

Answer 0

Spleen

Liver

Question 1

Leukemia rf

Answer 1

Adult
Male
Genetic disorders
Environment risks
Previous cancer tx

Question 2

Leukemia S/S

Answer 2

Spllenomegaly
Fatigue
Cns
Kid stones
Liver
High uric acid

Question 3

AML

Answer 3

Most common adult onset

Myeloblast and hyperplasia uncontrolled

Question 4

AML poor prog

Answer 4

Wbc > 100k

Cns involvement

Question 5

Induction

Answer 5

Kill the blasts taking over

Question 6

Induction drugs

Answer 6

Rubicens
Mynazantrone
Cytarabine

Question 7

Biopsy

Answer 7

Determine > 5% blast

Question 8

Post remission

Answer 8

Eradicate leftover bad cells

Necessary

Question 9

Antibiotics

Answer 9

Aminoglycosides

Pen derivative

Question 10

Hgb plt

Answer 10

> 8

> 10

Question 11

Cytarabine s/e

Answer 11

Hair loss
returns but different texture
Toxic to corneas (routine tears)

Question 12

Tumor lysis syndrome

Answer 12

Know

Question 13

Rubicins

Answer 13

Days 1-3
Cardio toxic
Hepato toxic
Very irritating

Question 14

ALL

Answer 14

Acute lymphocytic leukemia
B cell (85%)
Teens and children
Uncontrolled myeloblasts

Question 15

ALL good prognosis

Answer 15

No Down
White female
Responds to tx rapidly
B cell
Detected 1-9 yo

Question 16

Methotrexate

Answer 16

Leuko stomatitis anemia
Pulmonary fibrosis
Aplastic
Sj

Question 17

Leukovorin

Answer 17

Helps prevent renal toxicity and keep urine alkaline

Question 18

ALL

Answer 18

1-9

Wbc > 50

Question 19

All high risk

Answer 19

> 10 yo

> 50k

Question 20

CML

Answer 20

Chromosomal
15% all adult
More men
30-50yo
Asymptomatic
70% of cases become AML

Question 21

Chronic cml

Answer 21

< 10% blast cells

Question 22

Accelerated cml

Answer 22

10-19% blast cells

Question 23

Blast crisis cml

Answer 23

> 20% blast cells

Question 24

Gleevec

Answer 24

Exemplar

Question 25

Em

Answer 25

Siadh