2.1 A time line of genetics: from Darwin to DNA Flashcards
1853
Darwin publishes the ‘origin’
1853 - 1866
Mendel formulates laws of inheritance
1869
Friedrich Mescher isolates nucleic acids (‘nuclein’) from pus
1885
Strasburger and Flemming describe chromosomes
1900
Mendel’s work rediscovered
1902
Sutton + Bover’s chromosome theory of heredity
1904
Morgan’s experiments with Drosophila reveal mutations
1909
Johansson introduces the term ‘gene’
1928
Griffith discovers ‘transforming principle’ in bacteria
1944
Avery et al identify DNA as the ‘transforming principle’
1953
Hershey and Chase experiments:
DNA as the genetic material in phage T2
Watson and Crick propose a structure for DNA
1970s
Fred Sanger develops dideoxy sequencing
1972
Paul Berg constructs 1st recombinant DNA
1981
Human mtDNA sequenced
1986
Kary Mulls develops PCR