2050H Midterm Flashcards
Autosome
Paired chromosomes that have the same length/shape
Sex Chromosomes
Chromosomes with different length and shape
Name the different parts of Mitosis
INTERPHASE
G1 - Cell grows
S - DNA duplication
G2 - Cell prepared for Mitosis
M PHASE
Mitosis - Actual cell division
Cytokinesis - Cytoplasm splits
Name the sections of Chromatids and the different chromosome types
Telomere, centromere and then Metacentric, Submetacentric, Acrocentric, and Telocentric
Prophase
Chromones condense and mitotic spindle forms
Prometaphase
Nuclear membrane disintegrates and spindle fibers attach to chromatids
Metaphase
Chromosomes line up on metaphase plate
Anaphase
Sister chromatids separate and move towards opposite poles
Telophase
Chromosomes arrive at spindle poles and nuclear membrane reforms
Name the differences between Mitosis and Meiosis
Produces Gametes (4 daughter cells) and during metaphase II the chromosomes line up on equitorial plate.
Crossing over
The physical exchange of segments of non-sister chromatids that occurs in LATE PROPHASE 1
Independent assortment
Random Distribution of Paternal and Maternal chromosomes that occurs in METAPHASE II
What is G bonding
Karyotype preparation that shows A-T base pairs
What is R bonding
Karyotype preparation that shows C-G base pairs
What is Q bonding
Shows C-G vs A-T base pairs
What is C bonding
Shows the position of centromeres on chromosomes
What are duplications
When part of the chromosome is doubled
Tandem Duplication
Duplication is next to the original segment
Displaced duplication
Duplication is some distance from original segment
Reverse Duplication
The duplication is next to original segment and is reversed (EFFE)
Why do duplications affect phenotypes?
They have additional copies of normal sequences and therefore can cause dosage problems where more proteins are created which can cause abnormal development
What are deletions`
The loss of a chromosome segments