2021 PREP Flashcards
What diagnosis is supported by high fecal fat but normal pancreatic elastase?
Celiac disease (fat malabsorption but normal pancreatic function)
What complement levels are expected in PSGN?
Low C3 and normal C4
Which respiratory virus commonly causes acute hemorrhagic cystitis?
Adenovirus
Which OTC medication for abdominal pain is commonly associated with melenotic-appearing stools?
Bismuth subsalicylate (Pepto Bismol)
What is the treatment for bloody otorrhea from superficial trauma (i.e. curette use)?
Supportive care
What is the evaluation for medullary thyroid carcinoma in patients with MEN 2B?
Thyroid US and serum calcitonin levels
What are the phenotypes of MEN 1, MEN 2A, and MEN 2B?
What are the most common symptoms of maternal parvovirus B19 infection?
Lacy rash and arthralgias
Which congenital cardiac anomalies are associated with Turner syndrome?
Bicuspid aortic valve and coarctation of the aorta
Which lab abnormality is characteristic of urea cycle disorders?
Hyperammonemia
Which congenital abnormality is associated with clenched hands with overlapping fingers?
Trisomy 18
What are the hallmarks of physical exam in trisomy 13?
Cutis aplasia and midline defects
What is the definition of pubertal delay in boys?
Testicular volume < 4 mL by age 14
At what age can children be vaccinated against hepatitis A?
≥ 1 year of age
What is the required timeframe for administering immune globulin after a hepatitis A exposure?
Within 2 weeks
What is the preferred post-exposure prophylaxis against hepatitis A in children ≥ 1 year of age?
Hepatitis A vaccine
When is imaging indicated in children with genu valgus?
> 7 years of age with intermalleolar distances greater than 8 cm
Which bacteria most commonly cause infective endocarditis?
Strep viridans and Staph aureus
What is the difference in red reflex for cataracts and glaucoma?
Cataracts: usually unilateral
Glaucoma: bilateral clouding
What is the chance of passing on an X-linked recessive disorder to a male child?
50%
What is the difference between intention-to-treat and per-protocol analysis?
Intention-to-treat: includes all enrolled participants regardless of study completion (improves power because it increases N)
Per-protocol: includes only participants who completed the study
How can urinary anion gap help to differentiate between RTA and diarrhea?
Urinary ion gap = [Na + K] compared to Cl
Positive in RTA: [Na + K] > Cl
Negative in diarrhea: [Na + K] < Cl
How does obesity impact thyroid testing?
Artificially increases TSH
When should a statin be considered?
LDL ≥ 160 despite dietary and lifestyle changes
What is the treatment of persistent bacterial bronchitis?
Augmentin for 2-4 weeks
What is the difference in physical exam between acute flaccid myelitis and idiopathic transverse myelitis?
Acute flaccid paralysis: can be unilateral and affect 1+ limbs
Idiopathic transverse myelitis: bilateral
What is the primary treatment of Prader-Willi syndrome in the first year after life?
Growth hormone supplementation
What are the typical physical characteristics of patients with Prader-Willi syndrome?
Almond-shaped eyes, thin upper lip, small hands and feet
What is a potential significant adverse effect of hallucinogens?
Serotonin syndrome
Which nutritional deficiency is associated with goat milk ingestion in infants?
Folate deficiency
Which risk factor is associated with higher weight loss (~10%) in a neonate in the first 24-48 hours after birth?
Birth via CS
What is the difference in results of high-dose dexamethasone suppression test for pituitary vs. adrenal sources of excess cortisol?
Pituitary source: suppressed cortisol level
Adrenal source: no response
What is the appropriate post-exposure prophylaxis for varicella exposure by age and immune status?
< 12 months of age: no intervention
> 12 months of age and healthy: vaccine
Immunocompromised: immune globulin
What is the pathologic finding of sarcoidosis?
Non-caseating granulomas
What is the treatment of syphilis by stage?
Primary, secondary, and early latent: IM penicillin x1
Late latent and tertiary: IM penicillin once weekly x3 weeks
Which mutation causes fragile X syndrome?
CGG repeats in FMR1