2019 + 2018 Summative Flashcards
Screening for bowel cancer, which one is used
a. Faecal occult blood test
b. Do a full blood count
c. Check iron studies
d. Ask patient if they see any blood in stool
e. Stool microscopy for blood
a. Faecal occult blood test
67 year old man who comes in with his daughter. She is concerned about his decreased functioning at work. He also had a car accident recently where he misjudged the distance between his car and an oncoming car. Daughter says that he is not as happy as he usually is and that he “sees things” that she can’t see. He used to enjoy walking, but is walking less now and his walking has become slowed. He has no changes to his memory and these symptoms have been gradually worsening over the past few years.
What mechanism could have caused these symptoms?
a. Amyloid-beta aggregates
b. Alpha-synuclein aggregates
c. Multiple cortical infarcts
d. Prion Disease
e. Tau protein aggregates
b. Alpha-synuclein aggregates
Man presents with an absent gag reflex and when asked to cough it’s weak. What cranial nerve is likely to be affected?
a. Facial
b. Trigeminal
c. Accessory
d. Vagus
e. Hypoglossal
d. Vagus
26 year old man with dental abscess which needs to be surgically removed under local anaesthetic.
What would impact the effectiveness of the local anaesthetic?
a. Extent of inflammation.
b. Previous effects of local anaesthetics.
c. Injury to local nerves.
d. pH elevation in local tissues.
e. Nutritional status of the patient.
a. Extent of inflammation.
What is the pathogenesis of coeliac disease?
a. IgE mast cell
b. IgG
c. T cell mediated
d. Immune complex deposition of glucose and antibody
c. T cell mediated
Bilaterally reduced knee jerk reflex. What do you think is causing this?
a. Lesion in DCML
b. Lesion in motor cortex
c. Metabolic disturbance
d. Voluntary inhibition of reflex
d. Voluntary inhibition of reflex
A 67-year-old man with severe COPD is on many medications. He presents with dysphonia and has white plaques on his tongue and parapharyngeal area. Which of his medications could have caused this presentation?
a. Intermediate corticosteroid
b. Long-acting muscarinic antagonist
c. Long-acting sympathomimetic
d. Short-acting sympathomimetic
e. Short-acting muscarinic antagonist
a. Intermediate corticosteroid
In DKA, dehydration is common. What is the main mechanism by which this occurs?
a. Increased GFR
b. Excess sweating due to metabolic changes
c. Third spacing of fluid into the extracellular space
d. Increased urine output and electrolyte loss
e. Vomiting
d. Increased urine output and electrolyte loss
What is the leading cause of death in people aged 12-24 in Australia?
a. Accidental drug overdose
b. Anorexia nervosa
c. Cancer
d. Road traffic accidents
e. Suicide
e. Suicide
Left testicular swelling over two days. Is diagnosed with epididymo-orchitis. What is the most common organism that causes this?
a. E.Coli
b. Chlamydia t.
c. T. pallium
d. C albicans
e. Group B Streptococcus
b. Chlamydia t.
30M, presents to the hospital, they perform an endoscopy and find a duodenal ulcer. Post-op, what would make you most concerned that he now has severe GIT bleed?
a. Bradycardia
b. Haematemesis
c. Epigastric pain
d. Melaena
e. Slow capillary refill
e. Slow capillary refill
Hyperventilation is used to reduce increased Intracranial Pressure (ICP). What is the mechanism behind this?
a. Increased oxygenation
b. Increased RR increases perfusion of cerebral blood vessels
c. Hypocapnia causes vasoconstriction
d. Increased CO2 levels cause vasodilation
c. Hypocapnia causes vasoconstriction
Guy who has an overactive detrusor muscle. Which of the following drug classes would help?
a. Alpha-1 agonist
b. Beta-3 adrenergic agonist
c. Muscarinic M3 receptor agonist
d. Nicotinic receptor agonist
b. Beta-3 adrenergic agonist
What pathogen are neonates most susceptible to?
a. Encapsulated bacteria
b. Virus
c. Ecto Protozoa
d. protozoa
e. Non-Encapsulated bacteria
a. Encapsulated bacteria
Patient is started on and infusion of plain tap water at a rapid rate. What would this cause?
a. No significant change
b. High efflux water
c. High influx Na
d. Shrinkage and cretination
e. Swelling and haemolysis
e. Swelling and haemolysis
A patient who has oculomotor nerve palsy of one of their eyes will present with which of the following (for their affected eyes)?
a. Lateral and downwards
b. Lateral and upwards
c. Medial and downwards
d. Medial and upwards
a. Lateral and downwards
Loperamide is an opioid more potent than morphine. However, it is available as an over-the-counter medication for diarrhoea.
Why does it have a small effect on the CNS?
a. Converted to a lipid soluble metabolite
b. Efficiently transported by P-glycoprotein
c. Low affinity for CYP450 enzymes
d. Rapid uptake by enterocytes
b. Efficiently transported by P-glycoprotein
Which alteration in neurotramission is responsible for the anxiolytic action of diazepam?
a. 5-hydroxytryptamine
b. Gamma Aminobutyric acid
c. Increases glutamate
d. Inhibiting Gamma Aminobutyric acid
e. Inhibiting 5-hydroxytryptamine
b. Gamma Aminobutyric acid
Antipsychotics are associated with extrapyramidal side effects (EPSEs).
Which is true?
a. Clozapine is likely to have EPSEs
b. Second generation antipsychotics are more likely to have EPSEs than first generation
c. ESPEs worse with drugs with higher D2 receptor occupancy
d. EPSEs are caused by hyperdopaminergic state
e. Mydriasis is a common EPS
c. ESPEs worse with drugs with higher D2 receptor occupancy
A woman has been alcohol abstinent for the last five months. She attends a birthday party and has a slice of cake asking her friend, “what’s the secret to great cake”?. She is told that it is the addition of rum. She leaves the party worried. A short time later she feels flushed and develops a headache and nausea. What medication is she taking?
a. Acamprosate
b. Clozipine
c. Diazepam
d. Disulfiram
d. Disulfiram
You need to test the nerve pathways of the limbs. Which of the following tests would be most useful for testing the dorsal (posterior) column?
a. Testing blunt/sharp pain
b. Testing light touch
c. Testing vibration
d. Testing temperature
c. Testing vibration
What is the major contributor to the increase in CO during the first half of pregnancy?
a. Increase in vascular resistance
b. Decrease in vascular resistance
c. Increased HR
d. Increased SV
e. Decrease in preload
d. Increased SV
Which of the following is most likely sign of diabetic retinopathy?
a. Corneal abrasion
b. Poor pupillary response
c. Cloudy vitreous
d. Blot haemorrhage
e. Increased disk ratio
d. Blot haemorrhage
A 50 yo man complains of inability to obtain an erection. Has had some issues over the last year, but now completely unable to obtain erection in the last 6 months. Diagnosed with T2DM 3 years ago but has not been treating it. . Separated from wife 3 years ago, and started dating someone new 6 months ago. He is wondering if it is because of the vasectomy he had 5 years ago. What is the most likely cause of his erectile dysfunction?
a. Early relationship issues
b. Reduced prolactin from diabetes
c. Vascular changes from intermittent claudication
d. Middle-aged men usually have low testosterone levels
e. Side effect of vasectomy
c. Vascular changes from intermittent claudication
A 42 year old woman has a microadenoma of the pituitary leading to excess production of ACTH.
What clinical presentation would you expect to see?
a. Bone formation and increased density
b. Obesity and hypertension
d. Sodium and fluid retention
e. Tachycardia and tremors
b. Obesity and hypertension
Man is stabbed with a knife in the axilla region. He is unable to adduct thumb or abduct pinky. All else is normal, which nerve is severed?
a. Axillary nerve
b. Medial nerve
c. Musculocutaneous nerve
d. Radial nerve
e. Ulnar nerve
e. Ulnar nerve
You are a GP seeing a patient diagnosed with schizophrenia. They are an identical twin. What is the risk of the other twin developing schizophrenia?
a. 20%
b. 30-75%
c. 95%
d. No more risk than in non-twin siblings.
e. No more risk than any the general population
30-75%
On FBC the patient has increased RBC, decreased Haemoglobin, increased MCV.
a. Hereditary Spherocytosis
b. Thalassemia
c. Folate deficiency anaemia
d. Iron deficiency anaemia
c. Folate deficiency anaemia
where do most ectopic pregnancies occur?
fallopian tubes
Indication for monoamine oxidase inhibitors?
a. Constipation
b. Depression
c. Bipolar Disorder
d. Hypertension
b. Depression
Ductus venosus allows bypassing of:
a. Lungs
b. Liver
c. Lower limb
d. Pelvic organs
b. Liver
Lung cancer secreting ADH would have which effect:
a. Increased fluid in extravascular fluid
b. Low osmolality urine
c. Increased sodium reabsorption
d. Increased serum sodium.
c. Increased sodium reabsorption
Which of the following is true with regard to the containment of amniotic fluid?
a. Amnion is avascular
b. Chorion is inside the amnion
c. Mucus plug is the primary thing that stops fluid leakage
d. Amnion is directly against the foetus
a. Amnion is avascular
Pt on metformin and gliclazide (a sulphonylurea). Has a hypoglycemic episode. What has caused the hypoglycaemic episode?
a. Metformin for insulin release from beta cells
b. Metformin increases insulin sensitivity
c. Sulphonylurea for insulin release from beta cells
d. Sulphonylurea increases insulin sensitivity
c. Sulphonylurea for insulin release from beta cells
What’s true about the cervix?
a. The junction between ectocervix and endocervix occurs at the internal os
b. The cervix is mostly smooth muscle
c. The endocervical canal has tall columnar cells that secrete mucus
d. The endocervical canal connects the uterine cavity to the vulva
e. The vagina has tall columnar cells
c. The endocervical canal has tall columnar cells that secrete mucus
Woman is breastfeeding and hasn’t had her period yet. What’s the mechanism behind this?
a. Prolactin suppresses GnRH
b. Prolactin stimulates GnRH
c. Prolactin suppresses progesterone
d. Prolactin suppresses oestrogen
a. Prolactin suppresses GnRH
What neurotransmitter is implicated in social affiliation?
a. Dopamine
b. Serotonin
c. Oxytocin
d. Noradrenalin
e. Prolactin
c. Oxytocin
A pregnant woman’s waters have broken. What ruptured?
a. Placenta
b. Amniotic sac
c. Yolk sac
d. Chorion
b. Amniotic sac