2018 MCQ Flashcards
66 yo M presents to ED w/ angina pectoris. Admin med. which acts by releasing NO and his sx.s are relived. What is the most likely med?
GTN
twin-twin transfusion syndrome
Diagnosis requires 2 criteria
1. the presence of a MCDA pregnancy
2. presence of oligohydramnios (defined as a maximal vertical pocket of <2cm) in one sac AND of polyhydramnios (max. vertical pocket of >8cm) in the other sac
MCDA pregnancy
Monochorionic, diamniotic (MCDA)
- product of single fertilised egg= genetically identical twins
- share single placenta (Blood supply) but have separate amniotic sac
- Which of the following drugs is most likely to reduce mortality and morbidity in patients
with either diastolic or isolated systolic hypertension?
A. Calcium blockers
B. Thiazide-like diuretics
C. Alpha blockers
D. ACE inhibitors
E. Beta blockers
B
- note sure why answer isn’t CCB
- compared to CCBs or thiazide diuretics, ACEi/ ARBs have distinctly less efficacy in patients w/ isolated systolic HTN
Why is carbidopa used in the Tx of parkinson’s
Levodopa is converted to dopamine in the brain and peripheral tissue and replenishes the depleted striatal dopamine. It is given w/….
Carbidopa (or benserazide)= peripheral dopa decarboxylase inhibitor: To reduce the metabolism of L-Dopa in the periphery.
And therefore reduce production of dopamine in the periphery and also reduce adverse effects (e.g. nausea, vomiting, hypotension)
autograft, allograft, isograft, xenograft, technograft
Autograft: transplant to self from self
AllograftL transplant between genetically different ppl
IsograftL transplant btw genetically identical people
Xenograft: transplant btw different species
A previously well 14 month-old child, presents with a history of sudden onset of cough
and wheeze. He was playing with some toys earlier. On examination, there is evidence of
reduced air entry and wheeze over the right lung. Which of the following is the most likely
diagnosis?
A. Asthma
B. Bronchiolitis
C. Congenital airway abnormality
D. Inhaled foreign body
E. Pneumonia
D
Woman presents 10 weeks pregnant and gets a FBC, it shows a microcytic anaemia
and the blood film showed thalassemia B traits. The blood status of the partner is
unknown. What is the management?
Prevention of B thalassaemia major include:
- genetic counselling or antenatal diagnosis using fetal blood or DNA then ‘therapeutic’ abortion
28yo male with acute psychosis was admitted to the psychiatric ward for treatment for
10 days. Experienced sudden intense painful neck muscle cramping/stiffness and a
forward flexion of head. What is the drug that most likely caused his symptoms?
A. Benztropine
B. Fluoxetine
C. Haloperidol
D. Lithium
E. Olanzapine
and why
Haloperidol
- the pt has torticollis (dystonic EPSE)
-typical antipsychotics like haloperidol have more EPSEs than atypical e.g. olanzapine
what is it
pilonidal cyst (discomfort when sitting down, 23yo M)
35 y/o male feels anxious, gets tingling sensation in the lips (and other Sx) in certain
situations. He is worried to have these symptoms in front of others, therefore he avoids
crowded places. He is soon to be promoted to a higher position at work and wasn’t sure if
he could cope with it.
A. Generalised Anxiety Disorder
B. Panic Disorder
C. Social Phobia
D. Post-traumatic disorder
E. Depression
C
MoA donepezil
main therapeutic use is in alzheimer’s to increase cortical acetylcholine (acetylcholinesterase inhibitors)
30y/o lady, G2P2, comes in with 6 week old son for routine appointment. Has
symptoms of poor concentration, sleep, fatigue, loss of weight to below pre-pregnancy
weight. Vehemently denies being depressed, didn’t feel that way with first child. What is
the diagnosis?
A. Post natal depression
B. Post natal psychosis
C. Adjustment disorder
D. Baby blues
E. Persistent depressive disorder
A
23 year old married woman presents with vaginal discharge/pain. Dysuria but no
pruritus. On examination she has a raised painful inguinal lymph nodes with red ulcers on
both vulva and the cervix appears red and ulcerated. There is no malodour but profuse
clear discharge. Diagnosis?
Herpes genitalia
- genital herpes presents w/ panful genital ulcers vs primary syphilis presents w. painLESS ulcers (chancre)
7yo well, asymptomatic girl has loud pansystolic murmur, palpable thrill at left sternal
edge. Routine check. Heart sounds and apex beat otherwise normal. Diagnosis?
Ventricular septal defect (VSD)
- harsh pansystolic murmur at LSE w/ systolic thrill +/- L parasternal heave
19 yo male comes to GP very distressed. Worried about his nose, think’s it’s big and is
very conscious of it and wants to get plastic surgery because he looks at it in the mirror all
the time and he thinks the girls won’t like him because of it.
A. Body dysmorphic disorder
B. Delusional disorder
C. Micropenis
D. OCD
E. Congenital nasal hypertrophy
A
80 Year old female presents with sudden vision loss in left eye one hour ago. Over the
past week she has been having pain in her jaw when she chews. O/E she has tender,
enlarged superficial temporal arteries. What is the most appropriate immediate
management?
A. Temporal artery biopsy
B. Thombolytic therapy
C. Commence steroids
D. Cerebral angiogram
E. Urgent referral to ophthalmologist
C
GCA: start prednisolone 60mg/day PO immediately and do temporal aa bx w/in 14 days of starting steroids
20yo man brought into ED by housemates. Has rapid speech but could be interrupted.
Thought the Prime Minister was a robot sent from the future, like terminator, to kill him and
then destroy the human race. Diagnosis?
A. Mengele alogia
B. Grandiose Delusion
C. Persecutory delusion
D. Formal thought disorder
E. Projection
C
Young boy presented with sudden testicular pain. Felt nauseous and vomited.
Diagnosis?
A. Epididymitis
B. Testicular torsion
C. Hydrocoele
D. Varicocele
B
sudden onset of pain in ONE testis: makes walking uncomfortable
pain in abdo, n+v
28yo male presented with firm, non-tender intratesticular lump that is hypoechoic on
ultrasound. What do you do to confirm the diagnosis?
A. Inguinal orchiectomy
B. Trans-scrotal open biopsy
C. Trans-scrotal core biopsy
D. Fine needle aspirate
E. Serum B-HCG
why
A
when testicular cancer is suspected entire testicle is removed (orchiectomy)
testicular bx is NOT performed as a a part of evaluation due to concern that it may result in tumour seeding into the scrotal sac or mt.s into inguinal nodes
Pregnant woman completed first stage of labour in 7 hours, and second stage in 3
hours. She is well. What medication does she need now?
A. Syntocinon 10U IM
B. Syntocinon IV infusion
C. Ergometrine
syntocinon 10U IM
3rd stage of labour interventions
-The use of uterotonics are recommended for ALL births to prevent PPH (post partum haemorrhage)
-oxytocin 10IU IV/IM is recommended
35y/o female presented with a 2 year history of a slowly enlarging lump on her neck,
the mass is mobile and non tender, on the left side of her neck. She is euthyroid and
asymptomatic. Likely diagnosis is:
A. Hashimoto’s
B. Thyroid cancer
C. Simple thyroid cyst
D. Thyroid adenoma
E. Toxic multinodular goitre
simple thyroid cyst
A 30yo pregnant woman presents with premature rupture of membranes at 32 weeks.
She needs transfer to a more established hospital. In the meantime, what medications
should you give her?
vancomycin + flucloxacillin
9-month-old infant female presents distressed with proteins +++, nitrites +, leukocytes
+ on urine dipstick. She is febrile 38°C. What is the next single best step?
A. Renal USS
B. Cephalexin TDS
C. Wait until MCS to give antibiotics
D. Renal biopsy
B
30yoF BIBA after being in a fight with friends who were trying to stop her overdosing
on some medication. She has had 13 similar episodes previously. Her most notable
feature was her emotional lability. Diagnosis?
A. Borderline Personality disorder
B. Bipolar
C. Schizophrenia
D. Psychotic Depression
E. Premenstrual syndrome
A
What is the primary action of the COCP
inhibit ovulation
32yo male, Iraqi refugee who has been in Australia for 12 months. Presented to DEM
escorted by police after neighborhood disturbance. Has had four such presentations in the
last four weeks. States the Iraqi police are watching him through his TV and his body
feeling has changed. Also states insects buzzing around him so to rectify this he decided
to get rid of them via lighting ring of fire with petrol in his front yard. This is what resulted in
him being brought into ED, he had never been admitted under the psychiatry team before.
Also smokes marijuana 2-3 cones/week. Diagnosis?
A. Culture shock
B. Factitious disorder
C. Schizophrenia
D. Somatoform disorder
E. Substance abuse
C
Young female presents with copious milky discharge from her vagina. She also
noticed that there is a “foul fishy” smell. No clue cells on microscopy. Diagnosis?
A. Bacterial vaginosis
B. Candidiasis
C. Genital herpes
D. HPV
E. Chlamydia
WHY
A
bacterial vaginosis likely: thin, white d/c from vagina which is fishy smelling
candidiasis or vaginal trhush: creamy, thick (cottage cheese) d/c with no smell. Vulval irritation. Recnt Abs for sore throat.
Genital herpes: raised nodules that are painful.
Chlamydia: ost common asx
Young man feels worried about a lot of things. Seems to have no clear trigger on his
symptoms of palpitations, tremor and sweating. He is taking on a lot of responsibilities at
work however recently he has taken plenty of sick leave off work. Diagnosis?
A. Generalised Anxiety Disorder
B. Panic Disorder
C. Social Phobia
D. Post-traumatic disorder
E. Depression
A
16yo F complaints of irregular periods. Her menstrual cycle is 3-7 weeks long, and she
is concerned about her irregular bleeding. You note that she also has acne greasy skin
and a BMI of 24. What’s your management?
A. Start COCP
B. Start metformin
C. Lifestyle change
D. Start insulin
WHY
A
- address pt concern first and since it’s irregular bleeding- start COCP but ofc lifestyle changes and stuff are plausible options
Middle-aged woman presents wanting a script for the COCP. She is 6 months
postpartum, breastfeeding, has had a previous episode of DVT and suffers from migraine
without aura. Which is the absolute contraindication to COCP?
A. 6 months postpartum
B. Breastfeeding
C. Previous episode of DVT
D. Migraine without aura
previous DVT
A grandmother brings her child in. She is concerned about the injuries he sustained
when he was staying with his mother. The child appears to be on high alert. There are
some fingermark bruising on his arms and thighs. What should you do next?
A. Call child protection services
B. Call the police
C. Investigate the FBC and coagulation studies of the child
C
An infant had a difficult labour. The midwives decided to use forceps to aid delivery.
The infant then had a V-shaped bruise on forehead with image provided. Diagnosis?
forceps bruise
pregnant woman had a Caesarean section. 1 week after the operation, she
presented with offensive-smelling lochia. What is the diagnosis?
A. Endometritis
B. Wound infection
C. Retained products of conception
endometritis (lochia is vaginal d/c after birth)
young kid ate PB and has anaphylaxis- mx?
IM adrenaline
50 year old man comes into general practice for regular check-up. Asks about
screening for bowel cancer. No FHx and no symptoms. What would you suggest?
A. Colonoscopy
B. CT colonogram
C. FOBT
D. Flexible sigmoidoscopy
E. No screening required
C
Middle-aged man presents with sweating, weight loss of 6kg over past year and
tremor. Has two-year history of diffuse painless swelling at the base of neck. Examination
demonstrates mild tachycardia and fine peripheral tremor. Diagnosis?
A. Toxic multinodular goitre
B. Grave’s Disease
C. Toxic adenoma
D. Subacute thyroiditis
E. Hashimoto’s/autoimmune.
B
65 year old man presented with some shoulder pain and loss of range of abduction
(both passive and active) between 45 and 135 degrees. Movement was normal and pain
free from 0-45 and 135-180. What is the most likely pathology?
Rotator cuff pathology
what is CREST syndrome and what medication would improve peripheral circulation?
CREST
- calcinosis
-Reynaud’s
-eosophageal dymotility
-sclerodactyly
-telangiectasias (spider veins, visible small linear and red blood vessels)’
medication: nifedipine
diagnostic criteria for Kawasaki dx
fever for >5days+ at least 4 of the following:
- bilateral non-purulent conjunctivitis
- neck lymphadenopathy (>1.5cm across)
- pharyngeal injection, dry fissured lips, strawberry tongue
- polymorphous rash (especially on trunk)
- changes in extremities: arthralgia, palmar erythema or later fingertip desquamation+ swelling of hands/ feet
OCD vs OCPD
OCD: egodystonic
OCPD: (OC personality disorder or anakastic PD): egosyntonic
A 76 year-old female with known cardiomyopathy and poor left ventricular function,
presents to the Emergency Department with palpitations, dyspnoea at rest and dizziness.
Her pulse rate is 148/minute and irregularly irregular. Her ECG shows an irregularly
irregular rhythm with no P waves and normal QRS complexes. Which of the following drugs would be appropriate for long-term control of venticular rate? and why?
A. Digoxin
B. Verapamil
C. Metoprolol
D. Amiodarone
E. Adenosine
metoprolol
generally, for AF you do rhythm control for younger patients but rate control for older
A 45 year-old male presents to the Emergency Department with rapid regular
palpitations that came on while he was exercising. He is found to have a pulse rate of
148/minute and regular, with a BP of 105/60. His ECG shows a regular tachycardia with
no P waves and with normal QRS complexes. Which of the following drugs would be the
most appropriate for the acute management of this patient? and WHY
A. Digoxin
B. Verapamil
C. Metoprolol
D. Lignocaine
E. Adenosine
adenosine
- patient has supraventricular tachycardia
- adenosine is appropriate
A pregnant woman presented with rupture of membranes at 28 weeks. She was given
steroids and the baby was born 6 hours later. The neonate’s APGAR 1 minute was fine
but at 5 min, the neonate had respiratory distress. Diagnosis?
A. Hyaline membrane disease
B. Wet lung
C. Meconium aspiration
hyaline membrane dx
- pre-term babies
-given bethamethasone to try accelerate dev. of fetal lungs
-immature lungs; do not have adequate surfactant and therefore alveoli collapse
-respi distress start at or soon after delivery and get worse over the first 48 hrs
64yo male presented with right colicky loin to groin pain. Apart from fever (Temp =
38.8degC), physical examination was normal. Urinalysis revealed positive WCC and nitrites. CT showed 4mm stone and pelvic ureteric junction w/dilated ureter proximal to it. What is appropriate mx and why?
Urgent decompression
- 95% renal stones <5mm pass spontaneously by just increasing fluid intake HOWEVER, persistent infection and obstruction warrants urgent intervention.
Which of the following antibiotics is most appropriate for the treatment of a patient
infected with Shigella dysenteriae?
A. Flucloxacillin
B. Penicillin G
C. Ciprofloxacin
D. Fluconazole
E. Amoxicillin
shigella: ciprofloxacin
7yo boy presents with moderate SOB and moderate increased WOB. He has a past
history of asthma. SpO2 92% What is the initial management for the boy in the ED?
A. Nebulized SABA
B. Nebulized adrenaline
C. MDI SABA with spacer
and why
C
Guidelines recommend MDI SABA w/ spacer for mild-moderate asthma attacks. Only use nebulized salbutamol (SABA) if child is confused, exhausted w. silent chest
A child can roll over and sit with support. They can pass toys from one hand to the
other but don’t have pincer grip. They can drink from a bottle. They respond to their own
name, can babble but don’t yet have any words. They don’t have stranger anxiety.
Which option best describes the child’s developmental age:
A. 3 months
B. 6 months
C. 9 months
D. 12 months
E. 18 months
6 months
Middle-aged man presented with a small lesion on his cheek. A 1.5cm excisional
biopsy was done. How do you close the lesion up?
A. Direct closure
B. Local advancement flap
C. Free flap
D. Split skin graft
local advancement flap