2017 - Final XLS in CSV form - Sheet1 Flashcards

1
Q

What does treatment of GDM improve?

A

Lower rates of macrosomia

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2
Q

What is the most likely cause of fetal Macrosomia?

A

Prepregnancy obesity

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3
Q

Which ultrasound parameter predicts placenta accreta most accurately?

A

Lacunae

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4
Q

What is the best method to determine heart rate in the first trimester?

A

M- Mode

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5
Q

If maternal thyroid function is well controlled but fetus develops goiter. What test should you do?

A

Check maternal Thyroid Peroxidase Antibody; Thyroglobulin Antibody; Thyroid Stimulating Hormone Receptor Antibody (All synonyms for TSI)

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6
Q

When does fetal movement increase the most in a 24 hour period?

A

At night

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7
Q

After cardiac arrest, when should delivery ideally occur ?

A

Within 5 minutes (If spontaneous circulation does not occur within 4 mins of effective CPR)

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8
Q

What mutation happens in Duchenne Muscular Dystrophy?

A

Deletion of Exons (X-L-Recessive)

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9
Q

What is the mutation in Osteogenesis Imperfecta? Inheritance?

A

COL1A1 and COL1A2 (autosomeal dominant)

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10
Q

What is the mutation in Spinal Muscular Atrophy? Inheritance?

A

SMN1

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11
Q

What are the branches of the Internal Iliac Artery?

A
Midline structures and GiOPi
 Gluteal (Inferior)
 Obturator
 Pudendal (internal)
 Vagina
 Uterus
 Vesical
 Rectal (middle)
 Umbilical

Posterior Division: I love sex
Iliolumbar
Lateral Sacral
Superior Gluteal

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12
Q

What is the most effective anticoagulation for patients with mechanical heart valves?

A

Warfarin

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13
Q

Best medication for anticoagulation in pregnancy?

A

Lovenox

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14
Q

How do you differentiate betweem TTTS and TAPS?

A

MCA Dopplers (MCA PSV >1.5MoM in one twin and <0.8 MoM in the other twin )

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15
Q

What is more convincing situation to intubate, hypoxemia or hypercapnea?

A

Hypercapnea

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16
Q

Which Interleukin is antiinflammatory

A

IL10

17
Q

When is CVS not recommended?

A

In cases of Isoimmunizatio/Alloimmunization (NAIT, Kell, Rh)

18
Q

What is the most common symptom after a lumbar puncture ?

A

Headache that gets worse with standing/sitting and better with laying flat

19
Q

How do you diagnose NAIT?

A

In a baby with unexplained ICH or thrombocytopenia
1. test mom for platelet antibodie
2. if positive, test maternal and paternal antigens
NAIT = If Mom is antibody positive and dad is homozygous positive for that antigen
or if dad is heterozygous (test the fetus)

20
Q

What is the risk of NAIT in a subsequent pregnancy?

A

If father’s antigen zygosity determines he is homozygous: 100% risk
Heterozygous: 50% risk

21
Q

What product (of Aldosterone and testosterone) is increased in 21 hydroxylase deficiency, 17 hydroxylase deficiency and 11 hydroxylase deficiency

A

Follow the 1’s 1 = increase, BP - T
21 = BP down, Testosterone Up
17 = BP up, Testosterone down
11 = BP up, Testosterone up

22
Q

What are the criteria for pre-eclpamsia with severe features?

A
  1. BP: >160 systolic or >110 diastolic x 2, atleast 4 hours apart
  2. Plt <100,000
  3. ↑ LFTs + severe RUQ/epigastric pain 4. Cr > 1.1 or doubled 5. Pulmonary edema 6. New-onset headache not responsive to meds 7. Visual distubances
23
Q

What is the treatmet for TB?

A
  1. Rifampin
  2. Isonoazid
  3. Pyrazinamide
  4. Ethambutal
24
Q

Which TB treatment is teratogenic? What does it do?

A

Streptomycin is contraindicated - as it is associated with hearing loss

25
Q

What is the best study design to look at a disease and link to a risk factor? Example: smoking and cancer

A

Case control:

Compares a group with disease to a group without and looks back at risk factor

26
Q

Which medications to treat SLE are teratogenic?

A

Mycophenolate Mofetil and Cyclophosphamide

27
Q

What is the most common complication of SLE on pregnancy?

A
  1. Pre-eclampsia (8-20%)

2. PTD (spont and indicated - 20-50%) - Not spontaneous PTB

28
Q

If a preterm baby develops respiratory distress after delivery and Preductal SpO2: 90%, post ductal: 70%. What is the diagnosis?

A

Persistent fetal circulation (Ductus arteriosus) or PPHN (same thing)

29
Q

What are the abnormalities with acute fatty liver of pregnancy?

A

↑ LFTs, uric acid, billirubin , Ammonia

↓ Platelets, ↓ Glucose

30
Q

Which adrenergic receptors are present on the myometrium?

A
  1. α1: ↑ Phospholipase C -> ↑Protein Kinase C & Calsium 2. β2: ↑ Adenylyl Cyclase -> ↑ CAMP –> ↑ Protein Kinase A
31
Q

What effects on lipids does Depot Provera have?

A

↑ LDL

↓ HDL No change in triglycerides

32
Q

What is the most likely diagnosis of fetus with enlarged bladder?

A

Posterior uretheral valves is most common cause of bladder outlet obstruction

33
Q

What is the most common placental mass?

A

Chorioangioma - has color flow , associated with Polyhydramnios (60%) and IUGR (20%)