2017 - Final XLS in CSV form - Sheet1 Flashcards
What does treatment of GDM improve?
Lower rates of macrosomia
What is the most likely cause of fetal Macrosomia?
Prepregnancy obesity
Which ultrasound parameter predicts placenta accreta most accurately?
Lacunae
What is the best method to determine heart rate in the first trimester?
M- Mode
If maternal thyroid function is well controlled but fetus develops goiter. What test should you do?
Check maternal Thyroid Peroxidase Antibody; Thyroglobulin Antibody; Thyroid Stimulating Hormone Receptor Antibody (All synonyms for TSI)
When does fetal movement increase the most in a 24 hour period?
At night
After cardiac arrest, when should delivery ideally occur ?
Within 5 minutes (If spontaneous circulation does not occur within 4 mins of effective CPR)
What mutation happens in Duchenne Muscular Dystrophy?
Deletion of Exons (X-L-Recessive)
What is the mutation in Osteogenesis Imperfecta? Inheritance?
COL1A1 and COL1A2 (autosomeal dominant)
What is the mutation in Spinal Muscular Atrophy? Inheritance?
SMN1
What are the branches of the Internal Iliac Artery?
Midline structures and GiOPi Gluteal (Inferior) Obturator Pudendal (internal) Vagina Uterus Vesical Rectal (middle) Umbilical
Posterior Division: I love sex
Iliolumbar
Lateral Sacral
Superior Gluteal
What is the most effective anticoagulation for patients with mechanical heart valves?
Warfarin
Best medication for anticoagulation in pregnancy?
Lovenox
How do you differentiate betweem TTTS and TAPS?
MCA Dopplers (MCA PSV >1.5MoM in one twin and <0.8 MoM in the other twin )
What is more convincing situation to intubate, hypoxemia or hypercapnea?
Hypercapnea
Which Interleukin is antiinflammatory
IL10
When is CVS not recommended?
In cases of Isoimmunizatio/Alloimmunization (NAIT, Kell, Rh)
What is the most common symptom after a lumbar puncture ?
Headache that gets worse with standing/sitting and better with laying flat
How do you diagnose NAIT?
In a baby with unexplained ICH or thrombocytopenia
1. test mom for platelet antibodie
2. if positive, test maternal and paternal antigens
NAIT = If Mom is antibody positive and dad is homozygous positive for that antigen
or if dad is heterozygous (test the fetus)
What is the risk of NAIT in a subsequent pregnancy?
If father’s antigen zygosity determines he is homozygous: 100% risk
Heterozygous: 50% risk
What product (of Aldosterone and testosterone) is increased in 21 hydroxylase deficiency, 17 hydroxylase deficiency and 11 hydroxylase deficiency
Follow the 1’s 1 = increase, BP - T
21 = BP down, Testosterone Up
17 = BP up, Testosterone down
11 = BP up, Testosterone up
What are the criteria for pre-eclpamsia with severe features?
- BP: >160 systolic or >110 diastolic x 2, atleast 4 hours apart
- Plt <100,000
- ↑ LFTs + severe RUQ/epigastric pain 4. Cr > 1.1 or doubled 5. Pulmonary edema 6. New-onset headache not responsive to meds 7. Visual distubances
What is the treatmet for TB?
- Rifampin
- Isonoazid
- Pyrazinamide
- Ethambutal
Which TB treatment is teratogenic? What does it do?
Streptomycin is contraindicated - as it is associated with hearing loss
What is the best study design to look at a disease and link to a risk factor? Example: smoking and cancer
Case control:
Compares a group with disease to a group without and looks back at risk factor
Which medications to treat SLE are teratogenic?
Mycophenolate Mofetil and Cyclophosphamide
What is the most common complication of SLE on pregnancy?
- Pre-eclampsia (8-20%)
2. PTD (spont and indicated - 20-50%) - Not spontaneous PTB
If a preterm baby develops respiratory distress after delivery and Preductal SpO2: 90%, post ductal: 70%. What is the diagnosis?
Persistent fetal circulation (Ductus arteriosus) or PPHN (same thing)
What are the abnormalities with acute fatty liver of pregnancy?
↑ LFTs, uric acid, billirubin , Ammonia
↓ Platelets, ↓ Glucose
Which adrenergic receptors are present on the myometrium?
- α1: ↑ Phospholipase C -> ↑Protein Kinase C & Calsium 2. β2: ↑ Adenylyl Cyclase -> ↑ CAMP –> ↑ Protein Kinase A
What effects on lipids does Depot Provera have?
↑ LDL
↓ HDL No change in triglycerides
What is the most likely diagnosis of fetus with enlarged bladder?
Posterior uretheral valves is most common cause of bladder outlet obstruction
What is the most common placental mass?
Chorioangioma - has color flow , associated with Polyhydramnios (60%) and IUGR (20%)