2015 - Final XLS in CSV form - Sheet1 Flashcards

1
Q

Which autoimmune diseases are associated with RA factor?

A

Scleroderama, SLE, Sjogrens, RA and Dermatomyositis

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2
Q

Which cardiac anomaly most associated with DiGeorge ?

A

Interrupted aortic arch

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3
Q

In a patient with DiGeorge, what is the most common cardiac anomaly?

A

ToF

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4
Q

What is a prolonged aPTT in a patient with pre-eclampsia is most likely due?

A

APLS

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5
Q

Which lab measuring cardiac ischemia/function can be increased after vaginal delivery?

A

CKMB - found not only in myocardium but also in uterus and placenta.

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6
Q

Which artery can be injured when separating the rectus muscles during a c-section?

A

Inferior epigastric

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7
Q

Where can you find the ureter?

A

Over the bifurcation of the iliac artery

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8
Q

After a Fontan procedure, what does cardiac output depend most on?

A

Preload or SV

(HR plays a negligable role In a fontan circulation)

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9
Q

What is the mode of inheritance of familial hypertrophic cardiomyopathy?

A

Autosomal Dominant

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10
Q

What is the inheritance pattern of PKU?

A

Autosomal Recessive

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11
Q

What is mode of inheritance of Fragile X?

A

X linked dominant

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12
Q

Baby with nasal hypoplasia and limb defects?

A

Warfarin embryopathy

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13
Q

If a CVS shows balanced translocation, what should you do next?

A

Maternal karyotype

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14
Q

Which Doppler finding is the worst?

A

Reversed A wave in DV

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15
Q

How do you treat pregnancies at risk of NAIT?

And when do you deliver?

A

If previously affected with Thrombocytopenia and ICH IVIG @ 12 weeks - Del @ 35-36
If previously affected with thrombocytopenia but NO ICH @ 20 weeks Del @ 37-38
De

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16
Q

Which fetal organ system is most susceptible to teratogens earlier and for the longest time?

A

Brain

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17
Q

Does obesity increase risk of NTDs?

A

YES

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18
Q

Which factors move the Oxygen dissociation curve to the left?

A

Left means: Higher affinity of Hb-O2

  1. Fetal Hb
  2. Lower CO2
  3. Higher pH
  4. Lower temperature
  5. Lower 2-3 DPG
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19
Q

What is the most likely reason to intubate a pregnant lady?

A

Respiratory acidosis

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20
Q

Which Respiratory functions don’t change in pregnancy?

A
  1. Vital Capacity
  2. Respiratory Rate
  3. FEV1
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21
Q

Which antibody is positive if you have been vaccinated for Hep B?

A

Hep B surface antibody (anti-HBs)

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22
Q

Which tests are positive if you are chronically infected with Hep B?

A

Surface antigen and core antibody (anti-HBc)

23
Q

Where does fetus make blood throughout pregnancy?

A

Yolk sac: 3-8 weeks
Liver: 6 weeks -> birth
Spleen: 8 weeks -> 28 weeks
Bone marrow: 18 weeks -> adult

24
Q

Which uterine structural anomaly has the highest miscarriage rate?

A
#1. Septate 
 #2. Unicornuate 
 #3. Bicornuate
25
Q

Which uterine anomaly has the highest risk of PTL?

A
#1. Didelphys 
 #2. Bicornuate 
 #3. Septate
26
Q

What is the most common presentation of AFE?

A
  1. Hypoxia/Hypotension

2. Coagulopathy

27
Q

Which infertility treatment is associated with hypospadias ?

A

ICSI

28
Q

Clenched fists are associated with which chromosomal abnormality?

A

T18

29
Q

When is cardiac output the highest?

A

Immediately after delvery due to autotransfusion

30
Q

If a patient refuses CD for fetal indications, what should you do?

A

Continue taking care of patient and don’t proceed with CD. Respect patient wishes

31
Q

What is the most common adverse effect of general anesthesia?

A

Nausea and vomiting

32
Q

Which local anesthesic is least likely to cause neurotoxicity if given IV?

A

Lidocaine wont cause it,
Chloroprocaine will
and bupivicaine will but more cardiotoxic

33
Q

Why do you explain informed consent?

A

Autonomy

34
Q

Which ethical principle explains a Dr/Patient relationship?

A

Beneficence

35
Q

What are the key abnormalities with Meckel Gruber?

A

Post-axial Polydactyly
Multicystic Dysplastic Kidneys
Encephalocele

36
Q

Which drug prevents IVH?

A

BMZ - also decreases RDS, NEC and neonatal mortality

37
Q

Which hormone drops to allow breastfeeding?

A

Estrogen

38
Q

When is breastfeeding contraindicated?

A

HIV
Untreated Active TB
HSV Lesion Breast
Infants with classic galactosemia

39
Q

What pregnancy outcomes does bariatric surgery improve?

A

Gestational Diabetes

Less Macrosomia

40
Q

What is the most likely obstetrical complication related to obesity?

A

Increased Cesarean Delivery

41
Q

What is the most common complication of SLE on pregnancy?

A
  1. Pre-eclampsia (8-20%) 2. PTL (spont and indicated - 20-50%)
42
Q

Patient with SLE that has normal fetal anatomy but fetal heart rate noted in 60s. What is the likely cause?

A

Congenital heart block - from SSA and SSB antibodies

43
Q

Patient with elevated HbA1c (10%), what is the most likely finding on ultrasound?

A

Normal

44
Q

What would a biopsy of a pre-eclamptic patient show?

A

Glomeruloendotheliosis in Nulligravidas

Normal histologic appearance in multigravidas

45
Q

What causes diabetic retinopathy?

A

Chronic hyperglycemia - elevated HBA1c

46
Q

If a patient has class F diabetes, what are they at most risk of?

A
diabetic nephropathy
 #1Pre-eclampsia
 #2 PTD
 #3 Growth Restriction
47
Q

How do you differentiate between CCAM and CHAOS?

A

In Chaos you have inverted diaphragm

48
Q

What molecule gets degraded most by the placenta?

A

Prednisone/Prednisolone - by 11 β-hydroxysteroid dehydrogenase Type 2

49
Q

What drug is impermeable to the placenta?

A

Insulin, except if IgG bound

50
Q

What drug doesn’t cross the placenta

A

Heparin, and maybe insulin unless IgG bound.

51
Q

What hormone can increase maturation of lungs?

A

Betamethasone/Dexamethasone, Thyroxine, Vitamin A

52
Q

Which hormone decreases surfactant synthesis?

A

Insulin - delays surfactant production

53
Q

What is the most specific finding of NEC?

A

Pneumatosis - diagnosis of NEC is confirmed with gas in bowel wall on Xray