2015 - Final XLS in CSV form - Sheet1 Flashcards

1
Q

Which autoimmune diseases are associated with RA factor?

A

Scleroderama, SLE, Sjogrens, RA and Dermatomyositis

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2
Q

Which cardiac anomaly most associated with DiGeorge ?

A

Interrupted aortic arch

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3
Q

In a patient with DiGeorge, what is the most common cardiac anomaly?

A

ToF

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4
Q

What is a prolonged aPTT in a patient with pre-eclampsia is most likely due?

A

APLS

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5
Q

Which lab measuring cardiac ischemia/function can be increased after vaginal delivery?

A

CKMB - found not only in myocardium but also in uterus and placenta.

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6
Q

Which artery can be injured when separating the rectus muscles during a c-section?

A

Inferior epigastric

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7
Q

Where can you find the ureter?

A

Over the bifurcation of the iliac artery

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8
Q

After a Fontan procedure, what does cardiac output depend most on?

A

Preload or SV

(HR plays a negligable role In a fontan circulation)

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9
Q

What is the mode of inheritance of familial hypertrophic cardiomyopathy?

A

Autosomal Dominant

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10
Q

What is the inheritance pattern of PKU?

A

Autosomal Recessive

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11
Q

What is mode of inheritance of Fragile X?

A

X linked dominant

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12
Q

Baby with nasal hypoplasia and limb defects?

A

Warfarin embryopathy

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13
Q

If a CVS shows balanced translocation, what should you do next?

A

Maternal karyotype

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14
Q

Which Doppler finding is the worst?

A

Reversed A wave in DV

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15
Q

How do you treat pregnancies at risk of NAIT?

And when do you deliver?

A

If previously affected with Thrombocytopenia and ICH IVIG @ 12 weeks - Del @ 35-36
If previously affected with thrombocytopenia but NO ICH @ 20 weeks Del @ 37-38
De

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16
Q

Which fetal organ system is most susceptible to teratogens earlier and for the longest time?

A

Brain

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17
Q

Does obesity increase risk of NTDs?

A

YES

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18
Q

Which factors move the Oxygen dissociation curve to the left?

A

Left means: Higher affinity of Hb-O2

  1. Fetal Hb
  2. Lower CO2
  3. Higher pH
  4. Lower temperature
  5. Lower 2-3 DPG
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19
Q

What is the most likely reason to intubate a pregnant lady?

A

Respiratory acidosis

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20
Q

Which Respiratory functions don’t change in pregnancy?

A
  1. Vital Capacity
  2. Respiratory Rate
  3. FEV1
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21
Q

Which antibody is positive if you have been vaccinated for Hep B?

A

Hep B surface antibody (anti-HBs)

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22
Q

Which tests are positive if you are chronically infected with Hep B?

A

Surface antigen and core antibody (anti-HBc)

23
Q

Where does fetus make blood throughout pregnancy?

A

Yolk sac: 3-8 weeks
Liver: 6 weeks -> birth
Spleen: 8 weeks -> 28 weeks
Bone marrow: 18 weeks -> adult

24
Q

Which uterine structural anomaly has the highest miscarriage rate?

A
#1. Septate 
 #2. Unicornuate 
 #3. Bicornuate
25
Which uterine anomaly has the highest risk of PTL?
``` #1. Didelphys #2. Bicornuate #3. Septate ```
26
What is the most common presentation of AFE?
1. Hypoxia/Hypotension | 2. Coagulopathy
27
Which infertility treatment is associated with hypospadias ?
ICSI
28
Clenched fists are associated with which chromosomal abnormality?
T18
29
When is cardiac output the highest?
Immediately after delvery due to autotransfusion
30
If a patient refuses CD for fetal indications, what should you do?
Continue taking care of patient and don't proceed with CD. Respect patient wishes
31
What is the most common adverse effect of general anesthesia?
Nausea and vomiting
32
Which local anesthesic is least likely to cause neurotoxicity if given IV?
Lidocaine wont cause it, Chloroprocaine will and bupivicaine will but more cardiotoxic
33
Why do you explain informed consent?
Autonomy
34
Which ethical principle explains a Dr/Patient relationship?
Beneficence
35
What are the key abnormalities with Meckel Gruber?
Post-axial Polydactyly Multicystic Dysplastic Kidneys Encephalocele
36
Which drug prevents IVH?
BMZ - also decreases RDS, NEC and neonatal mortality
37
Which hormone drops to allow breastfeeding?
Estrogen
38
When is breastfeeding contraindicated?
HIV Untreated Active TB HSV Lesion Breast Infants with classic galactosemia
39
What pregnancy outcomes does bariatric surgery improve?
Gestational Diabetes | Less Macrosomia
40
What is the most likely obstetrical complication related to obesity?
Increased Cesarean Delivery
41
What is the most common complication of SLE on pregnancy?
1. Pre-eclampsia (8-20%) 2. PTL (spont and indicated - 20-50%)
42
Patient with SLE that has normal fetal anatomy but fetal heart rate noted in 60s. What is the likely cause?
Congenital heart block - from SSA and SSB antibodies
43
Patient with elevated HbA1c (10%), what is the most likely finding on ultrasound?
Normal
44
What would a biopsy of a pre-eclamptic patient show?
Glomeruloendotheliosis in Nulligravidas | Normal histologic appearance in multigravidas
45
What causes diabetic retinopathy?
Chronic hyperglycemia - elevated HBA1c
46
If a patient has class F diabetes, what are they at most risk of?
``` diabetic nephropathy #1Pre-eclampsia #2 PTD #3 Growth Restriction ```
47
How do you differentiate between CCAM and CHAOS?
In Chaos you have inverted diaphragm
48
What molecule gets degraded most by the placenta?
Prednisone/Prednisolone - by 11 β-hydroxysteroid dehydrogenase Type 2
49
What drug is impermeable to the placenta?
Insulin, except if IgG bound
50
What drug doesn’t cross the placenta
Heparin, and maybe insulin unless IgG bound.
51
What hormone can increase maturation of lungs?
Betamethasone/Dexamethasone, Thyroxine, Vitamin A
52
Which hormone decreases surfactant synthesis?
Insulin - delays surfactant production
53
What is the most specific finding of NEC?
Pneumatosis - diagnosis of NEC is confirmed with gas in bowel wall on Xray