2013-10-23 Intro to Transfusion Medicine Flashcards
Blood cell transfusion depends on pt’s __________ _________.
plasma antibodies
How might an incorrect transfusion kill someone?
wrong trans -> DIC -> bleed out -> death
Plasma transfusion depends on pt’s ________ _________.
RBC antigens
Type A
- RBC surface antigens
- plasma ab’s
Type A
- A-antigen on surface
- Anti-B IgM in blood
Type B
- RBC surface antigens
- Plasma Ab’s
Type B
- B-antigens on surface
- Anti-A IgM
Type AB
- RBC Surface antigen
- Plasma Ab’s
Type AB
- A & B surface antigens
- no IgM
Type O
- RBC surface antigen
- plasma Ab’s
Type O
- no RBC surface antigens
- both Anti-A and Anti-B IgM in plasma
Who is universal blood donor?
Type O
Who is universal blood recipient?
AB
What type is universal plasma donor?
Type AB
Who is universal plasma recipient?
type O
How do you “type” blood?
Two ways:
FOWARD: “What RBCs antigens does my pt have?”
—mix blood w/ Anti-A, Anti-B, and Anti-AB; score 1-4 (4 = plug)
BACKWARD: “What plasma antibodies does my pt have?”
—mix plasma + reagent red cells
How does one “cross-match” blood?
mix PT’s PLASMA with DONOR’s RBCs
1) Pt presents with confusion, chest pain and Hb of 3.6. What is okay to transfuse? A. Type O RBCs B. Type AB RBCs C. Type O plasma D. Type AB Plasma
A
- 2) Pt s/p hip transplant with Type A and Hb of 6.5 (DHMC transfuses when Hb
C