2012 Flashcards

1
Q

commonest cause of mitral sten

A

rheumatic fever

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2
Q

how does mitral stenosis cause AF

A

volume and pressure of blood in LA increases
atrium larges
causes AF

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3
Q

starling forces in heart failure

A

increased hydrostatic pressure in vessels (pressure build up)
low oncotic pressure in veseels due to low albumin

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4
Q

4 main risk factors for pancreatitis

A
GET S
gallstones
ethanol
trauma - incl ERCP
SMOKING!!
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5
Q

what is the Allen’s test checking

A

adequate collaterals!
(hyperaemia of WHOLE hand on release of one artery)
checks both are patent and providing collateral blood supply

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6
Q

4 main risk factors for pancreatitis

A
GET S
gallstones
ethanol
trauma - incl ERCP
SMOKING!!
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7
Q

what is the Allen’s test checking

A

adequate collaterals!
(hyperaemia of WHOLE hand on release of one artery)
checks both are patent and providing collateral blood supply

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8
Q

drug used to treat hypercalcaemia?

drug MOA? inhibitis osteoclastic boen resorption

A

(NB IV 0..9% saline 4-6 L in 24 hr)

IV zolindronate

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9
Q

investigation to dx addison’s

A
short synacthen (synthetic ACTH) test -->
plasma cortisol is measured before and 30 minutes after giving IM Synacthen 250ug

Failure for cortisol to rise of >420nmol/L at 30 minutes post Synacthen indicates Addison’s disease

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10
Q

define hospital acquired infection

A

-infections acquired in hospital or healthcare service unit
-1st appears >=48h after admission OR
within 30 days of discharge
-unrelated to original illness that brings pt to hospital
-not present at time of admission

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11
Q

how to prevent spread of infection

A

isolation
gown and gloves
hand washing
appropriate and prompt use of Abx

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12
Q

define hospital acquired infection

A

-infections acquired in hospital or healthcare service unit
-1st appears >=48h after admission OR
within 30 days of discharge
-unrelated to original illness that brings pt to hospital
-not present at time of admission

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13
Q

how to prevent spread of infection

A

isolation
gown and gloves
hand washing
appropriate and prompt use of Abx

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14
Q

3 mark question why chosen SSRI

A

i think the ans could be

1st line drug, lower side effect profile than others, relatively safe in overdose

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15
Q

labile mood and weight loss

A

hyperthyroidism

frontal lobe brain tumour

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16
Q

causes of thrombocytopenia

A
aplastic anaemia
MDS
leukaemia
ITP
things with splenomegaly (porthal hypertesnsion, cirrhosis, myelofibrosis, viral infections e.g. CMV, EBV
17
Q

complications of infectious mononucleosis

A

encephalitis, meningoencephalitis, seizures, optic
neuritis, sudden sensorineural hearing loss, idiopathic
facial palsy, and Guillain-Barré syndrome

haemolytic anaemia (3%) and thrombocytopenia
(25-50%),

myocarditis, pericarditits

pancreatitis,
interstitial pneumonia, rhabdomyolysis,

18
Q

pathophysiology of splenomegaly

A
  • Congestive, by pooled blood (e.g., portal hypertension)
  • Infiltrative, by invasion by cells foreign to the splenic environment (e.g., metastases, myeloid neoplasms, lipid storage diseases)
  • Immune, by an increase in immunologic activity and subsequent hyperplasia (e.g., endocarditis, sarcoidosis, rheumatoid arthritis)
  • Neoplastic, when resident immune cells originate a neoplasm (e.g., lymphoma)
19
Q

signs of EBV on mouth eaxm

A

exudate

petechiae on roof of mouth (sometimes)

20
Q

pathophysiology of splenomegaly

A

Congestive, by pooled blood (e.g., portal hypertension)
Infiltrative, by invasion by cells foreign to the splenic environment (e.g., metastases, myeloid neoplasms, lipid storage diseases)
Immune, by an increase in immunologic activity and subsequent hyperplasia (e.g., endocarditis, sarcoidosis, rheumatoid arthritis)
Neoplastic, when resident immune cells originate a neoplasm (e.g., lymphoma

21
Q

look at the levels of burns

A

-

22
Q

treatment of thrombocytopenia EBV

A

IV steroids if severe

23
Q

fhx chronic leukaemia

A

CLL - 2-4x more likely

CML - FHx not relevant