20. Hypothalamus 1 Flashcards
Where is hypothalamus located?
Under thalamus at the base of the brain
What structure connects the hypothalamus to the posterior pituitary?
Infundibulum
Neural pathway connects?
Hypothalamus to PP
Vascular link connects?
Hypothalamus to AP
Embryological origin of anterior pituitary?
Epithelium of pharynx (Rathke’s Pouch)
Embryological origin of posterior pituitary?
Neural tissue from hypothalamus
What does the direct/portal route between the hypothalamus and AP permit?
Hypothalamus hypophysiotropic hormones to act immediately on AP cells before getting diluted/destroyed in general circulation
Order of flow of Hypophyseal System?
Artery → Capillary bed of median eminence → Portal vessel → Capillary bed of adenohypophysis → Vein
Where are neurohormones produced?
Hypothalamus
What do Somatotropes secrete?
GH
What do Corticotropes secrete?
ACTH Adrenocorticotropic Hormone
What do Thyrotropes secrete?
TSH
What do Gonadotropes secrete?
FSH + LH
What do Lactotropes secrete?
PRL
What regulates release of AP hormones?
- Hypothalamic hypophysiotropic hormones
2. Feedback by target hormones
Where is ADH typically formed?
SON
Where is Oxytocin typically formed?
PVN