2. STROKE Flashcards

1
Q

Define

Stroke

A

A stroke is a very serious condition where the blood supply to part of your brain is cut off. It needs to be treated in hospital as soon as possible.

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2
Q

Stroke

Symptoms

A

The main symptoms of stroke can be remembered with the word FAST:
Face – the face may have dropped on 1 side, the person may not be able to smile, or their mouth or eye may have dropped.

Arms – the person with suspected stroke may not be able to lift both arms and keep them there because of weakness or numbness in 1 arm.

Speech – their speech may be slurred or garbled, or the person may not be able to talk at all despite appearing to be awake; they may also have problems understanding what you’re saying to them.

Time – it’s time to dial 999 immediately if you see any of these signs or symptoms.

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3
Q

Stroke types 3

A

Transient ischemic attack (mini stroke)

Ischemic stroke (blood clot obstructs)

Hemorrhagic stroke (blood vessel burst)

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4
Q

Stroke pts lifestyle advice

A
Diet
Exercise 
Stop smoking 
Weight loss
Alcohol intake
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5
Q

Stroke

Ischaemic stroke

Long term Managment non AF related

A

Clopidogrel

Statin

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6
Q

Stroke

Ischaemic stroke

Long term Managment AF related

A

Review anticoagulant
Statin
Warfarin or other NOAC

rivaroxaban (brand names include Xarelto)
dabigatran (brand names include Pradaxa)
apixaban (brand names include Eliquis)
edoxaban (brand names include Lixiana)

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7
Q

Stroke

Transient stroke (mini stroke)

Long term Managment

A

MR Dipryidamole 200mg BD

+

Aspirin 75mg OD

+

Statin

(Avoid BB unless other condition)
treat hypertension

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8
Q

Stroke

Haemorrhage stroke

Long term Managment

A

Avoid

Aspirin, statin, anticoagulants ( give only if absolutely essential)

Treat hypertension & avoid hypoperfusion

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9
Q

Anti-platelet drugs in atrial circulation

And not anticoagulant why?

A

Clots in atrial circulation are made of platelets = anti platelets are good

Clots in veins slow moving are made of factors ( clots in veins, slow moving)
= anticoagulant are good here

Antiplatelets interfere with the binding of platelets, or the process that actually starts the formation of blood clots.

Anticoagulants interfere with the proteins in your blood that are involved with the coagulation process. These proteins are called factors. Different anticoagulants interfere with different factors to prevent clotting

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10
Q

Common antiplatelets include:

A
clopidogrel
ticagrelor 
prasugrel 
dipyridamole
dipyridamole/aspirin 
ticlopidine 
eptifibatide
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11
Q

anticoagulant examples

A
heparin
warfarin 
rivaroxaban (Xarelto)
dabigatran 
apixaban 
edoxaban 
enoxaparin 
fondaparinux
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12
Q

anticoagulant or antiplatelet drugs

SE

A

increased bruising
red or pink colored urine
stools that are bloody or look like coffee grounds
more bleeding than normal during your menstrual period
purple toes
pain, change in temperature, or blackish areas in your fingers, toes, hands, or feet

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13
Q

Aspirin 75 OD

Given to stroke pts why?

A

Secondary prevention Of CVD

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14
Q

What has to be stabilised BEFORE aspirin given to MI pts

A

Blood pressure controlled first!

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15
Q

Aspirin is CI in under 16yrs

Exemption in?

A

Is used as anti platelet

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16
Q

Dipyridamole tablets are given as a secondary prevention of stroke after or suffered a stroke, how to take?

Persantin retard CAPS?

A

30-60 mints BEFORE food

Persantin retard caps special container, 6 weeks expiry

17
Q

Clopidogrel 75 OD following what?

A

Acute coronary syndrome or PCI

18
Q

What to give if clopidogrel CI

A

MR dipyridamole + aspirin

Or

MR dipyridamole alone