2. Beta Blockers Flashcards
Be A MAN
Cardioselective therefore less btonchospasm therefore can be given to stable asthma pts if no other option available
B - bisoprolol
A - atenolol
M - metoprolol
A - acebutol
N - nebivolol
Beta blocker
What is it
What does it Tx
Beta blockers, also called beta adrenergic blocking agents, block the release of the stress hormones adrenaline and noradrenaline in certain parts of the body. This results in a slowing of the heart rate and reduces the force at which blood is pumped around your body.
Tx for:
angina, heart failure and some heart rhythm disorders, and to control blood pressure.
BB
CI
asthma; cardiogenic shock; hypotension; marked bradycardia; metabolic acidosis; phaeochromocytoma (apart from specific use with alpha-blockers); Prinzmetal’s angina; second-degree AV block; severe peripheral arterial disease; sick sinus syndrome; third-degree AV block; uncontrolled heart failure
Never give a BB with this rate limiting CCB
Verapamil
Injection or oral both! Avoid!!!
Can cause asystole flatline
CANS
Water soluble
Reduce dose in re al patients
Less SE Nightmares, less sleep disturbance
Doesn’t cross BBB
C - celiprolol
A- atenolol
N - nadalol
S - SOTALOL
Beta blockers
List
atenolol bisoprolol carvedilol. esmolol. metoprolol nebivolol (in hypertension 70+) propranolol
Insulin dependent diabetes + BB
Can cause:
the symptoms of hypoglycemia
Non insulin dependent diabetes + BB
Can cause
increase blood glucose concentrations and antagonize the action of oral hypoglycemic drugs.
BB - groups
1 BACN
2 ice PACO
3 CANS
4 Be A MAN
1 given only once a day
2 less SE extremities, bradycardia
3 water soluble doesn’t cross BBB, no nightmares
4 cardioselective, give asthma
BACN
these BB given only ONCE daily due to LONG duration of action
Most BB given as BD or TDS
B- bisoprolol
A- atenolol
C- celiprolol
N- nadolol
Best BB to give in diabetic pts
Carvedilol
ice PACO
Less SE of
cold extremities & less risk of bradycardia
P - pindolol
A - acebutol
C - Celiprolol
O - oxprenolol
BB
SE
Abdominal discomfort; bradycardia; confusion; depression; diarrhoea; dizziness; dry eye (reversible on discontinuation); dyspnoea; erectile dysfunction; fatigue; headache; heart failure; nausea; paraesthesia; peripheral coldness; peripheral vascular disease; rash (reversible on discontinuation); sleep disorders; syncope; visual impairment; vomiting