2- Rheumatology Concepts Flashcards
What are the 2 main categories of arthritis?
Inflammatory
Non-inflammatory (osteoarthritis)
What are the subdivisions of inflammatory arthritis?
Seropositive
Seronegative
Infectious
Crystal-induced
Give examples of seropositive arthritis
Rheumatoid arthritis Lupus Scleroderma Vasculitis Sjogren's syndrome
Give examples of seronegative arthritis
Ankylosing spondylitis
Psoriatic arthritis
Reactive arthritis
IBD arthritis
Autoantibody-related rheumatological conditions tend to be referred to as seronegative. True/False?
False Seropositive (autoantibodies are in the serum!)
Which antibodies are associated with rheumatoid arthritis?
Anti-CCP
Which diseases are associated with anti-nuclear antibody (ANA)?
SLE Sjogren's syndrome Systemic sclerosis Mixed CTD Autoimmune liver disease
Which antibodies are highly specific for SLE?
Anti-dsDNA
Anti-Sm
Which diseases are associated with Anti-Ro antibody?
SLE
Sjogren’s syndrome
Which antibody is highly specific for Sjogren’s syndrome?
Anti-La
Which antibody is associated with limited systemic sclerosis?
Anti-centromere
Which antibody is associated with diffuse systemic sclerosis?
Anti-Scl-70
Which diseases are associated with anti-RNP antibody?
SLE
Mixed CTD
Which antibody is specific for myositis?
Anti-Jo-1
Which antibodies/immunological factors are associated with anti-phospholipid syndrome?
Anti-cardiolipin antibody
Lupus anticoagulant