2- Rheumatology Concepts Flashcards

1
Q

What are the 2 main categories of arthritis?

A

Inflammatory

Non-inflammatory (osteoarthritis)

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2
Q

What are the subdivisions of inflammatory arthritis?

A

Seropositive
Seronegative
Infectious
Crystal-induced

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3
Q

Give examples of seropositive arthritis

A
Rheumatoid arthritis
Lupus
Scleroderma
Vasculitis
Sjogren's syndrome
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4
Q

Give examples of seronegative arthritis

A

Ankylosing spondylitis
Psoriatic arthritis
Reactive arthritis
IBD arthritis

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5
Q

Autoantibody-related rheumatological conditions tend to be referred to as seronegative. True/False?

A
False
Seropositive (autoantibodies are in the serum!)
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6
Q

Which antibodies are associated with rheumatoid arthritis?

A

Anti-CCP

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7
Q

Which diseases are associated with anti-nuclear antibody (ANA)?

A
SLE
Sjogren's syndrome
Systemic sclerosis
Mixed CTD
Autoimmune liver disease
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8
Q

Which antibodies are highly specific for SLE?

A

Anti-dsDNA

Anti-Sm

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9
Q

Which diseases are associated with Anti-Ro antibody?

A

SLE

Sjogren’s syndrome

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10
Q

Which antibody is highly specific for Sjogren’s syndrome?

A

Anti-La

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11
Q

Which antibody is associated with limited systemic sclerosis?

A

Anti-centromere

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12
Q

Which antibody is associated with diffuse systemic sclerosis?

A

Anti-Scl-70

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13
Q

Which diseases are associated with anti-RNP antibody?

A

SLE

Mixed CTD

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14
Q

Which antibody is specific for myositis?

A

Anti-Jo-1

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15
Q

Which antibodies/immunological factors are associated with anti-phospholipid syndrome?

A

Anti-cardiolipin antibody

Lupus anticoagulant

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16
Q

Which antibody is associated with small vessel vasculitis?

A

ANCA