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2MB MSK CORTEXT > 2- Myopathies > Flashcards

2- Myopathies Flashcards

1
Q

The aetiology of polymyalgia rheumatica (PMR) is unknown. True/False?

A

True

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2
Q

List clinical features of PMR

A

Hip and shoulder pain
Morning stiffness lasting longer than 1hr
Improvement with movement/throughout the day

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3
Q

Which arteritic condition is associated with PMR?

A

Giant cell arteritis

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4
Q

PMR responds really well to what treatment?

A

Low-dose steroid (prednisolone)

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5
Q

What is the most common form of systemic vasculitis in adults?

A

Giant cell arteritis

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6
Q

List clinical features of GCA

A 
Jaw claudication
Visual disturbance
Headache
Tender scalp
Systemic features
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7
Q

What is the definitive test for diagnosing GCA?

A

Temporal artery biopsy

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8
Q

How do polymyositis and dermatomyositis differ?

A

Essentially the same but dermatomyositis has skin changes

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9
Q

Polymyositis is more common in men. True/False?

A

False

Women 2:1 men

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10
Q

Is muscle weakness in polymyositis symmetrical?

A

Yes

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11
Q

List clinical features of polymyositis

A

Proximal muscle weakness
Myalgia
Difficulty with stairs
Dysphagia (poor prognostic sign)

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12
Q

By how much is CK usually raised in polymyositis?

A

10x

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13
Q

Which autoantibodies are associated with polymyositis?

A

ANA
Anti-Jo-1
Anti-SRP

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14
Q

What is the definitive diagnostic test for polymyositis?

A

Muscle biopsy

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15
Q

Outline treatment for polymyositis

A

Prednisolone 40mg

Immunosuppression

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16
Q

List some cutaneous features of dermatomyositis

A

Heliotrope rash
Gottron’s papules
V-shaped rash over chest

17
Q

In which group of people is fibromyalgia most common in?

A

Young and middle-aged women

18
Q

List clinical features of fibromyalgia

A

Persistent widespread pain (3+mths)
Fatigue, broken sleep
Cognitive impairment
Depression

19
Q

The mainstay of treatment for fibromyalgia is education and behavioural therapy. What drugs may be given?

A

Amitryptilline

Gabapentin

2MB MSK CORTEXT (22 decks)

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