2: Raynaud's disease Flashcards

1
Q

What is Raynaud’s phenomenon

A

excessive vasoconstriction of arterioles and arteries of the hand in response to cold or emotional stressor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How can the aetiology of Raynaud’s phenomenon be divided

A

primary and secondary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is another term for primary Raynaud’s phenomenon

A

Raynaud’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is secondary Raynaud’s phenomenon referred to as

A

Raynaud’s phenomenon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are 5 causes of Raynaud’s phenomenon

A
Medications (COCP, Ergot)
Connective tissue disease 
Cold agglutinins 
Cervical rib 
Type I cryoglobulinaemia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what connective tissue disorders may cause Raynaud’s disease

A

Scleroderma
SLE
RA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the most common cause of secondary raynaud’s phenomenon

A

Scleroderma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

in which demographic does primary raynaud’s often present

A

Young females

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how does primary raynaud’s typically present

A

Bilateral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

in which age group does secondary raynaud’s present

A

> 40y

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how does secondary raynaud’s present

A

Unilateral. Presence of other features such as rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the three phases of raynaud’s disease

A
  1. Ischaemic
  2. Hypoxic
  3. Hyperaemic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how does the ischaemic phase of raynaud’s present

A

White hands - presents with ischaemia, pallour, numbness, parasthesia and pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how does the hypoxic phase of raynaud’s present

A

Blue hands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how does the hyperaemic phase of raynaud’s present

A

Erythematous hands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how long do spasms typically last in raynaud’s

A

15-20m after stressor has been removed

17
Q

how is raynaud’s disease investigated

A

Clinical diagnosis

18
Q

how is raynaud’s phenomenon investigated

A

Depends on features of underlying disorder. Should include a medication review

19
Q

Who should be referred to a rheumatologist with Raynaud’s

A

everyone with secondary raynaud’s

20
Q

What is first line management for raynauds

A

Lifestyle:

  • Gloves for hands + feet
  • Smoking cessation
  • Reduce stress
  • Exercise
21
Q

What is first line pharmacological management for Raynaud’s

A

Nifedipine

22
Q

What is nifedipine

A

Calcium channel blocker

23
Q

What can be used as prophylaxis in Raynaud’s disease

A

IV prostacyclin (epoprostenole)