[2] Pathology of Lung Diseases, Injury, and Infections Flashcards
What is Atelectasis
Collapse of previously inflated lung creating airless pulmonary parenchyma
3 Types of Atelectasis
Resorption/Obstruction
Compression
Contraction
Resorption atelectasis causes a shift in of the mediastinum towards which direction?
Towards atelectatic lung
Compression atelectasis causes a shift in of the mediastinum towards which direction?
Away from the affected lung
This type of Atelectasis cannot be reversed
Contraction Atelectasis
What kind of atelectasis is caused by an obstruction or blockage?
Resorption Atelectasis
Common type of Emphysema found in smokers
Centriacinar (Centrilobular) Emphysema
This type of Emphysema is frequently the underlying lesion of spontaneous pneumothorax
Distal Acinar (Paraseptal) Emphysema
This type of Emphysema is commonly associated with Anti Trypsin 1 Deficiency
Panacinar (Panlobular) Emphysema
What would happen if a “bleb” was so paper-thin that it
ruptured?
Pneumothorax
Single histologic change in all abscesses
Suppurative destruction of lung parenchyma within central area of cavitation
First case of SARS was in which country?
China
Virus responsible for SARS
Coronavirus
Differentiate lobar pneumonia and bronchopneumonia grossly
Lobar: Consolidation of a large portion/entire lobe
Bronchopneumonia: Patchy consolidation
Differentiate lobar pneumonia and bronchopneumonia microscopically
You cannot distinguish them under a microscope
A more virulent organism will cause what lobar or bronchopneumonia?
Lobar Pneumonia
An immunocompromised host will cause get lobar or bronchopneumonia?
Lobar Pneumonia
Enumerate 4 Possible Complications of Pneumonia
- Microabscess
- Emphysema Thoracis
- Pleural Effusion
- Bacteremia/Sepsis
- Consolidation
[Common Bacterial Agents Isolated]
Children
Haemophilus B
[Common Bacterial Agents Isolated]
Adults
Strep. Pneumoniae
[Common Bacterial Agents Isolated]
COPD
Streptococcus
Moraxella
[Common Bacterial Agents Isolated]
Alcoholics
Klebsiella
[Common Bacterial Agents Isolated]
Elderly
Streptococcus
Legionella
3 Bacterial Agents that can present as Interstitial Pneumonia
Mycoplasma pneumonia
Chlamydia trachomatis
Coxiella burnetti
Most common fungal agent that may cause pneumonia
Aspergillus
Components of a Ghon Complex
Ghon Focus
Hilar Lymphadenopathy
Hallmark of Tuberculous Lesions
TB Granuloma
Gold Standard Diagnostic Modality for PTB
TB Culture and Isolation
Differentiate Langhans Type from other Giant Cell Types
Langhans: Nuclei arranged in a U-Shaped Pattern peripherally
Clinical Definition of Chronic Bronchitis
Persistent cough with sputum production for at least 3 months in 2 consecutive years
