[2] Pathology of Lung Diseases, Injury, and Infections Flashcards

1
Q

What is Atelectasis

A

Collapse of previously inflated lung creating airless pulmonary parenchyma

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2
Q

3 Types of Atelectasis

A

Resorption/Obstruction
Compression
Contraction

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3
Q

Resorption atelectasis causes a shift in of the mediastinum towards which direction?

A

Towards atelectatic lung

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4
Q

Compression atelectasis causes a shift in of the mediastinum towards which direction?

A

Away from the affected lung

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5
Q

This type of Atelectasis cannot be reversed

A

Contraction Atelectasis

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6
Q

What kind of atelectasis is caused by an obstruction or blockage?

A

Resorption Atelectasis

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7
Q

Common type of Emphysema found in smokers

A

Centriacinar (Centrilobular) Emphysema

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8
Q

This type of Emphysema is frequently the underlying lesion of spontaneous pneumothorax

A

Distal Acinar (Paraseptal) Emphysema

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9
Q

This type of Emphysema is commonly associated with Anti Trypsin 1 Deficiency

A

Panacinar (Panlobular) Emphysema

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10
Q

What would happen if a “bleb” was so paper-thin that it

ruptured?

A

Pneumothorax

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11
Q

Single histologic change in all abscesses

A

Suppurative destruction of lung parenchyma within central area of cavitation

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12
Q

First case of SARS was in which country?

A

China

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13
Q

Virus responsible for SARS

A

Coronavirus

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14
Q

Differentiate lobar pneumonia and bronchopneumonia grossly

A

Lobar: Consolidation of a large portion/entire lobe

Bronchopneumonia: Patchy consolidation

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15
Q

Differentiate lobar pneumonia and bronchopneumonia microscopically

A

You cannot distinguish them under a microscope

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16
Q

A more virulent organism will cause what lobar or bronchopneumonia?

A

Lobar Pneumonia

17
Q

An immunocompromised host will cause get lobar or bronchopneumonia?

A

Lobar Pneumonia

18
Q

Enumerate 4 Possible Complications of Pneumonia

A
  1. Microabscess
  2. Emphysema Thoracis
  3. Pleural Effusion
  4. Bacteremia/Sepsis
  5. Consolidation
19
Q

[Common Bacterial Agents Isolated]

Children

A

Haemophilus B

20
Q

[Common Bacterial Agents Isolated]

Adults

A

Strep. Pneumoniae

21
Q

[Common Bacterial Agents Isolated]

COPD

A

Streptococcus

Moraxella

22
Q

[Common Bacterial Agents Isolated]

Alcoholics

A

Klebsiella

23
Q

[Common Bacterial Agents Isolated]

Elderly

A

Streptococcus

Legionella

24
Q

3 Bacterial Agents that can present as Interstitial Pneumonia

A

Mycoplasma pneumonia
Chlamydia trachomatis
Coxiella burnetti

25
Q

Most common fungal agent that may cause pneumonia

A

Aspergillus

26
Q

Components of a Ghon Complex

A

Ghon Focus

Hilar Lymphadenopathy

27
Q

Hallmark of Tuberculous Lesions

A

TB Granuloma

28
Q

Gold Standard Diagnostic Modality for PTB

A

TB Culture and Isolation

29
Q

Differentiate Langhans Type from other Giant Cell Types

A

Langhans: Nuclei arranged in a U-Shaped Pattern peripherally

30
Q

Clinical Definition of Chronic Bronchitis

A

Persistent cough with sputum production for at least 3 months in 2 consecutive years