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Boards Path - Pathologic Markers > 2. Path Markers - Path > Flashcards

2. Path Markers - Path Flashcards

1
Q

Pathologic Markers for Prostate Cancer

A
  • PSA

- Prostatic acid phosphatase

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2
Q

PSA

A

Prostate specific antigen

  • Used to screen for prostate carcinoma
  • Can also be elevated in BPH and Prostatitis
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3
Q

Prostatic Acid Phosphatase

A
  • Marker of prostate carcinoma
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4
Q

CEA

A

Carcinoenbyonic antigen

  • Very non-specific
  • Most colorectal and pancreatic cancers
  • Some gastric, breast, and thyroid medullay carcinomas
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5
Q

Pathologic Marker for Non-Seminomatous Germ Cell Testicular Tumors (Yolk Sac Tumor)

A

a-fetoprotein

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6
Q

a-fetoprotein

A
  • Marker for Non-Seminomatous Germ Cell Testicular Tumors (Yolk Sac Tumor)
  • Low levels seen in Down’s syndrome
  • High levels seen in neural tube defects
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7
Q

Pathologic Marker for Hydatidiform Moles

A

b-HCG

- Levels also increased in Choriocarcinoma and Gestational trophoblastic tumor

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8
Q

b-HCG

A

Human Chorionic Gonadotropin
- Marker for Hydatidiform moles, Choriocarcinomas, and Gestational trophoblastic tumors

“HCG = Hydatidiform moles, Choriocarcinoma, Gestational trophoblastic tumor”

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9
Q

Pathologic Marker for Choriocarcinoma

A

b-HCG

- Levels also increased in Hydatidiform moles and Gestational trophoblastic tumor

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10
Q

Pathologic Marker for Gestational Trophoblastic Tumor

A

b-HCG

- Levels also increased in Choriocarcinoma and Hydatidiform moles

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11
Q

Pathologic Marker for Ovarian Cancer

A

CA-125

- Levels also increased in malignant epithelial tumor

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12
Q

Pathologic Marker for Malignant Epithelial Tumors

A

CA-125

- Levels also increased in Ovarian cancer

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13
Q

CA-125

A

Marker for Ovarian cancer or Malignant epithelial tumor

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14
Q

Pathologic Marker for Melanoma

A

S-100

- Levels also increased in Neural tumors and Schwannomas

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15
Q

Pathologic Marker for Neural Tumors

A

S-100

- Levels also increased in Melanoma and Schwannomas

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16
Q

Pathologic Marker for Schwannoma

A

S-100

- Levels also increased in Neural tumors and Melanoma

17
Q

S-100

A

Marker for:

  • Melanoma
  • Neural tumors
  • Schwannomas
18
Q

Pathologic Marker for Bone Metastases

A

Alkaline Phosphatase

- Levels also elevated in Obstructive biliary disease and Paget’s of the bone

19
Q

Pathologic Marker for Obstructive Biliary Disease

A

Alkaline Phosphatase

- Levels also elevated in Bone metastases and Paget’s of the bone

20
Q

Pathologic Marker for Paget’s of the Bone

A

Alkaline Phosphatase

- Levels also elevated in Obstructive biliary disease and Bone Metastases

21
Q

Alkaline Phosphatase

A

Marker for:

  • Metastases to the bone
  • Obstructive biliary disease
  • Paget’s of the bone
22
Q

Pathologic Marker for Neuroblastoma

A

Bombesin

- Levels also elevated in lung and gastric cancer

23
Q

Pathologic Marker for Lung Cancer

A

Bombesin

- Levels also elevated in Neuroblastoma and Gastric cancer

24
Q

Pathologic Marker for Gastric Cancer

A

Bombesin

- Levels also elevated in Neuroblastoma and Lung cancer

25
Q

Bombesin

A

Marker for:

  • Neuroblastoma
  • Gastric Cancer
  • Lung Cancer
26
Q

Pathologic Marker for Hairy Cell Leukemia

A

TRAP
- Tartrate-resistant acid phosphatase

“TRAP the HAIRY animal”

27
Q

TRAP

A
  • Tartrate-resistant acid phosphatase

- A marker for Hairy cell leukemia - a B cell neoplasm

28
Q

Pathologic Marker for Pancreatic Adenocarcinoma

A

CA-19-9

29
Q

CA-19-9

A

Marker for Pancreatic adenocarcinoma

30
Q

Pathologic Marker for Thyroid Medullary Carcinoma

A

Calcitonin

31
Q

High Calcitonin Levels

A

Marker for Thyroid Medullary Carcinoma

32
Q

Psammoma Bodies

A

Marker for:

  • Papillary thyroid adenocarcinoma
  • Serous papillary cystadenocarcinoma of the ovary
  • Meningioma
  • Malignant mesothelioma

“PSaMMoma = Papilly thyroid adenocarcinoma, ovarian Serous papillary cystadenocarcinoma, Meningioma, Mesothelioma”

33
Q

Pathologic Marker for Papillary Thyroid Adenocarcinoma

A

Psammoma Body
- Also seen in Ovarian serous cystadenocarcinoma, Meningioma, Mesothelioma

“PSaMMoma = Papilly thyroid adenocarcinoma, ovarian Serous papillary cystadenocarcinoma, Meningioma, Mesothelioma”

34
Q

Pathologic Marker for Ovarian Serous Cystadenocarcinoma

A

Psammoma Body
- Also seen in Papillary thyroid adenocarcinoma, Meningioma, Mesothelioma

“PSaMMoma = Papilly thyroid adenocarcinoma, ovarian Serous papillary cystadenocarcinoma, Meningioma, Mesothelioma”

35
Q

Pathologic Marker for Meningiomas

A

Psammoma Body
- Also seen in Papillary thyroid adenocarcinoma, Ovarian serous cystadenocarcinoma, Mesothelioma

“PSaMMoma = Papilly thyroid adenocarcinoma, ovarian Serous papillary cystadenocarcinoma, Meningioma, Mesothelioma”

36
Q

Pathologic Marker for Mesothelioma

A

Psammoma Body
- Also seen in Papillary thyroid adenocarcinoma, Ovarian serous cystadenocarcinoma, Meningioma

“PSaMMoma = Papilly thyroid adenocarcinoma, ovarian Serous papillary cystadenocarcinoma, Meningioma, Mesothelioma”

Boards Path - Pathologic Markers (2 decks)

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