2 - connective tissue Flashcards
functions of connective tissue
- energy storage
- structural role
- mediates exchange of metabolites,nutrients + waste between tissue + circulatory system
- houses immune cells
- force transmission - muscle force transmitted to skeleton in way other than origin + insertion
fibroblasts
- FOUND IN CONNECTIVE TISSUE
- synthesis extracellular matrix
- tissue repair
macrophages
- large white blood cells - derived from monocytes
- phagocytose foreign bodies
- secrete enzymes + cytokines
- process + present antigen for recognition by T cells
mast cells
- INFLAMMATION
- secrete histamine + bradykinin - induce inflammation
plasma cells
-synthesis + secrete antibodies
can only produce single kind of antibody - but produce several thousand per second
collagen 1
- bones
- tendons
- ligaments
- dermis
collagen 2
main protein in cartilage
collagen 3
reticular fibres - protect + support
collagen 4
main collagen component of basal lamina
collagen 5
-fibril-forming
collagen 7
-anchoring fibrils - link to basal lamina
reticular fibres
- type 3 collagen
- form branched supporting network
- only visible w/ silver staining
- first to form during wound healing
ground substance
- contains :
- glycosaminoglycans - highly sulfated, complex polysacharides
- proteoglycans - long chains of disacharide repeating units
- glycoproteins - short highly branched glycan chains w/ NO repeating units
loose / areolar connective tissue
- many cells
- thin collagen 3 fibres
- forms propria lamina , a thin layer of loose CT beneath epidermis
- forms mesentry - tissue attaching intestines to posterior abdominal wall
dense connective tissue
- few cells
-few ground substance
-thick collagen 1 fibres
IRREGULAR = dermis of skin, organ capsules
REGULAR = tendons, ligaments
embryonic connective tissue
mesenchyme tissue - progenitor for all adult CT cells
undifferentiated cells, uniformly distributed in abundant ground substance
mucous tissue - matrix of umbilical cord, cushions large blood vessels
