2- Collection and Physical Examination of Urine Flashcards
Def: Inspecified, can be collected at any time (Types, Timing of collection)
Random
most common use of random is for
screening purposes
type of collection that can sometimes give an inaccurate view of a patient’s health
Random
Def: first voided the urine is generally more concentrated (Types, Timing of collection)
First morning
First morning collection aka
8-houre specimen
First morning , contains relatively higher levels of
cellular elements, or protein
Def: voided after 8 hours of fasting (Types, Timing of collection)
Fasting-second
Def: voided is before a meal, and to collect a specimen 2 hours after eating
(Types, Timing of collection)
Postprandial-first
Def: is collection of urine measures creatinine, urine urea nitrogen, glucose, sodium, potassium (Types, Timing of collection)
Timed
Timed collection aka
24 hour collection
Def: urine is the preferred type of specimen for bacteria culture and sensitivity testing
(Types, Timing of collection)
Midstream Clean Catch
Midstream Clean Catch is preferred because of
reduced incidence of cellular and microbial contamination
Refrigeration or chemical preservation of urine specimens should be utilized within ____ hours
2
most common Urine Preservatives
Boric acid
T/F
Preserved urine specimens can be stored at room temperature until time of testing
Ture
Physical Examination of Urine includes
Appearance
Specific gravity
Volume
the pigment that gives urine it’s characteristic yellow color
Urochrome
Urochrome aka
urobilin
contribute some pink or reddish color to urine
Uroerythrin
Normal urine color variations (list the possible colors)

Abnormal urine color variations White can be pathologic due to
Chyle
Lipids
Pyuria
Define Chyle
milky body fluid consisting of lymph and emulsified fats, or free fatty acids
Define Pyuria
Increased WBCs
Abnormal urine color variations White can be NON-pathologic due to
Phosphates
Vaginal creams
Abnormal urine color variations
Yellow to amber to orange - pathogenic
Liver Dysfunction
chemotherapy drugs
Liver Dysfunction can cause excessive
urobilin or bilirubin
Abnormal urine color variations
Yellow to amber to orange, NON-pathogenic
Carrots
dehydration
Food color
Vit B complex or C
Carrots contains
beta carotene

Abnormal urine color variations
Yellow to green
Pathologic
Biliverdin
Bilirubin
Abnormal urine color variations
- *Yellow to green**
- *NON**-Pathologic
Asparagus

Abnormal urine color variations
Pink to red
Pathologic causes
Red blood cells
Hemoglobin
Myoglobin
Porphyrin

Abnormal urine color variations
Pink to red
Non-Pathologic causes
Beets
Food color
Abnormal urine color variations
Red to purple
Pathologic causes
Porphyrin

Abnormal urine color variations
are there any non-pathologic causes for “Red to purple” color
No
only pathologic
Abnormal urine color variations
Red to brown
pathologic causes
Methemoglobin
Myoglobin

Abnormal urine color variations
Red to brown
Non-Pathologic causes
none
only pathogenic
Abnormal urine color variations
Brown to black
Pathologic causes
Bilirubin
Methemoglobin
Myoglobin
Melanin
Homogentisic acid (alkapton)

Abnormal urine color variations
Brown to black
Non-Pathologic causes
Iron compounds
fava beans
aloe

Abnormal urine color variations
Blue to green
Pathologic causes
Biliverdin (green color)
Pseudomonas infection
Abnormal urine color variations
Blue to green
Non-Pathologic
Vitamin B12
Thymole
Diuretic therapy (blue urine color)
Clarity of urine
Normal urine is usually ____
clear
Cloudy urine may contain
salts /crystals
Hazy urine may contain
mucus
Smoky urine may contain
RBCs
Turbid urine may contain
leukocytes
bacteria
pus
proteins
epithelial cells
Milky urine may contain
fat or chyle
Various non-urinary substances can cause urine
specimens to appear
hazy or cloudy
Clear urine pathologic causes
Very dilute
Polyuria (DM, or DI)
Clear urine Non-pathologic causes
Over-hydrated
Hazy to cloudy to turbid urine pathologic causes

Varying degrees of
Casts
Cells
Crystals and calculi
Fat (lipid, chyle)
Microorganisms
Fecal contamination
Hazy to cloudy to turbid urine non-pathologic causes

Creams, lotions
Crystals
Mucus
Radiographic dyes
Powders
Fecal contamination
Pathologic causes for foamy urine

Significant amounts of protein (kidney disease)
UTI (e.g. pus)
Fistula from colon to bladder
Non-pathologic causes for foamy urine
Rapid urination
Foam increased with urine concentration (e.g. dehydration)
Toilet cleaner
Pathologic foamy urine persistently
become (more/less) noticeable over
time
more noticeable over time
Sweet or “fruity” odor casued by
Ketones (e.g. DM)
Pungent odor casued by
bacteria (ammonia) (e.g. UTI)
“maple syrup” odor casued by
amino acids
“musty or mousy” odor of an infant’s urine casued by
Phenylketonuria
“Rancid butter” or “fishy” odor casued by
Hypermethioninemia
stronger ammonia odor casued by
Dehydration
define Urine Specific Gravity (USG)
Ratio of the weight of urine to the weight of the same volume of distilled water at a constant
temperature

USG Used to measure the
concentrating
diluting ability of the kidney
one of the first functions to be lost as a result of tubular damage
Concentrating ability
Normal USG range
1.003–1.035
In Refractive Index, we use a tool called
Total Solids (TS) Meter (refractometer)
degree of deviation or refraction is proportional to ____
the density of the solution.
Refractive index varies with ___
Temprature
Specific Gravity Reagent Strips actually measures ____
ionic concentration

Specific Gravity Reagent Strips Indicator measures the change in ____
pH
When urine has an increased specific gravity, the reagent pad becomes more _____
acidic
Urine Osmolality depends on ______
The number of particles in the solution
whereas specific gravity depends on
the number and weight of the solutes
Osmolality is a better indicator of the concentrating and diluting abilities of the kidney, because
it’s unaffected by the density of solutes.
In pathological urines, what type of measurement of urine osmolality should be used?
direct measurement