2 Cells and Communication Flashcards
Neuron vs Neuroglial cells
Neurons: can’t be replaced, function in communication
Neuroglial: can replicate (mitosis), outnumber neurons, play a variety of roles in support, injury, and disease of the NS
CNS Neuroglia and function
Astrocytes - Blood Brain Barrier
Oligodendrocytes - Myelinate
Microglia - Macrophage
Ependymal Cells - CSF
PNS Neuroglia and function
Schwann Cells - Myelinate
Satellite Cells - PNS ganglia metabolism
Can peripheral n regenerate?
Depend on if cell body intact and extent of damage
Explain Neurapraxia (Class I)
Mildest, caused by compression
Explain Axonotmesis (Class II)
Axon damaged, CT intact
Explain Neurotmesis (Class III)
Transection of axon (axon & CT)
Graded potential vs Action potential
Graded: Can be summed (spatial/temporal)
Action: Can’t be summed (all-or-none + refractory period)
Spatial summation vs Temporal summation
Spatial: Multiple neuron firing (across space)
Temporal: 1 neuron firing multiple potential (over time)
How neurons communicate?
Action Potential -> Neurotransmitters released -> bind to receptor