2- AP and the Synapse Flashcards
RMP (voltage)
-70 to -90 mV
Properties of AP
Threshold
All or nothing opening of VG Na channels
Conduction without decay
AP is followed by refractory
Purpose of Refractory Period
Ensures forward movement of AP (polarity)
Conduction Velocity in Unmyelinate Axons Determined By
Diameter
Large diameter= faster
Synthesis of Small Molecule NTs
In axon terminal
i.e. ACh by ChAT
Synthesis of Peptide NT
Synthesized in cell body and transported to terminal
Gap Junctions
Made up of connexons
No NT needed (electrically coupled)
Neuron Impermeable to
Ca
Na
Neuron Permeable to
Cl
K
Advantage of Gap Junction
No delay in transmiting info
Useful for neurons that need to fire synchrounously
Don’t need NT
Disadvantage of Gap Junction
Loss of individuality
One cell fires= all fire