2: Acute Mesenteric Ischaemia, Chronic Mesenteric Ischaemia, Abdominal Trauma Flashcards
What is acute mesenteric ischaemia
Sudden decrease in blood supply to the bowl that can cause infarction
What are the 4 types of acute mesenteric ischaemia
- Acute mesenteric arterial thrombosis
- Acute mesenteric arterial embolism
- Venous congestion
- Non-occlusive ischaemia
If ischaemia due to thrombosis in situ what is it called
Acute mesenteric arterial thrombosis (AMAT)
if ischaemia is due to embolism in situ what is it called
Acute mesenteric arterial embolism (AMAE)
What is a cause of acute mesenteric arterial thrombosis
Atherosclerosis
What are 5 causes acute mesenteric arterial embolism
- AF
- AAA
- Thoracic AA
- Mural thrombus
- Prosthetic heart valve
What are 2 causes of non-occlusive mesenteric ischaemia
- Cardiogenic shock
2. Hypovolaemic shock
What are 3 causes of venous occlusion
- Coagulopathy
- Thrombophilia
- Malignancy
What are risk factors for AMAT and AMAE
Cardiovascular RF: Smoking Alcohol HTN Hypelripidaemia
How does acute mesenteric ischaemia present
- Pain out of proportion to clinical findings
- Diffuse, generalised abdominal pain
- N+V
What investigations are ordered for acute mesenteric ischaemia
- ABG
- CT scan with contrast
- CXR
What will be seen on ABG
- High lactate
- Metabolic acidosis
What imaging is used to definitely diagnose acute mesenteric ischaemia
CT with IV contrast
When is a CXR performed
If perforation is suspected
How is mesenteric ischaemia managed
IV Fluids
Broad-spec antibiotics
Surgery for re-vascularisation (with re-look 24-48h after)
Revascularisation
What are 3 complications of mesenteric ischaemia
Bowel necrosis
Bowel perforation
Short-gut syndrome post-resection
What is chronic mesenteric ischaemia
reduced blood supply to the bowel due to atherosclerosis
In which individuals does chronic mesenteric ischaemia occur
Elderly patients
What are 4 risk factors for chronic mesenteric ischaemia
Smoking
Hyperlipidaemia
HTN
DM
How does chronic mesenteric ischaemia present
Post-prandial pain (10m-4h)
Weight loss
Explain pathophysiology of chronic mesenteric ischaemia
- Due to atherosclerosis of two blood vessels (SMA, IMA, Coeliac trunk). Due to collateral blood supply it must be 2.
- Bowel receives sufficient oxygen at rest, however, struggles during increased demand: such as post-digestion.
What is first-line investigation for chronic mesenteric ischaemia
CT angiography
What is gold-standard for acute mesenteric ischaemia
CT with contrast
What is used to manage chronic mesenteric ischaemia
Modify risk factors
Endovascular repair = mesenteric angioplasty
Which sites are vulnerable to ischaemia and why
Watershed areas:
Splenic flexure and rectosigmoid junction
- due to switch in blood supply
Define acute mesenteric ischaemia
ischaemia of the small intestine
Define ischaemic colitis
ischaemia of the large intestine
What causes ischaemic colitis
caused by global hypo perfusion caused by:
- Hypotension
- Hypovolaemia
- Thrombophillia
how does ischaemic colitis present
Presents in 3 phases
- Hyperactive
- Paralytic
- Shock
how does the hyperactive phase of ischaemic colitis present
Colicky abdominal pain in the LIF.
how does the paralytic phase of ischaemic colitis present
- Diffuse abdominal pain
- Bloating
- Absent bowel sounds
how does the shock phase of ischaemic colitis present
- Acute abdomen
- Guarding
- Rebound tenderness
how is acute mesenteric ischaemia investigated
CT W/constrast
how is ischaemic colitis investigated
CT angiography
how is ischaemic colitis managed
IV Fluids
Antiplatelets
- If necrotic may require resection