2

Question 1

Anti-CD30 ADC that cab cause JCV reactivation and PML

Answer 1

Brentuximab vedotin

Question 2

Ann arbor staging for primary nidal lymphoma

Answer 2

Limited:
St 1 - one node or a group of adjacent nodes
-single extranodal lesions without nodal involvement

St 2 - 2 or more nodal groups on the same side of the diaphragm
- st 1 or 2 by nodal extent with limited contiguous extranodal involvement

St 3- nodes on both sides of the diaphragm
- nodes above the doaphgram with spleen involvement

St 4- additional non-contiguous extralymphatic involvement

Question 3

Most common subtypes of B-cell lymphomas in PWH (3)

Answer 3

DLBCL
BL
PCNSL

Question 4

First line therapy for HIV positive DLBCL

Answer 4

R-EPOCH

Question 5

what to do after PET negative after 4 cycles of RCHOP early non bulky DLBCL-

Answer 5

Surveillance

Question 6

ART can ve safely administered with chemotherapy. However, avoidance of these 3 ART are strongly recommended

Answer 6

Zidovudine
Covicistat
Ritonavir