2 Flashcards
1
Q
Produce alpha chain when active
A
Interleukin-2 receptor
2
Q
In activated T-helper cells, DAG activates …………… which act to generate the transcription factors
A
Protein Kinase C
3
Q
PIP is split by…………….. to yield DAG and IP3
A
Phospholipase C
4
Q
The co-stimulatory signal needed for complete T-helper cell activation is triggered by
interaction of…….. on T-cells with B7 on APC
A
CD28
5
Q
Activation of T-helper cells results in the secretion of……… leading to activation
A
IL-2
6
Q
Calcineurin……….. involved in generating the active form of the transcription factor NF-AT
A
Ca dependent enzyme
7
Q
……… is a T-cell membrane receptor that has phosphatase domains activity
A
CD45
8
Q
Fyn and Lck are……..
A
Tyrosine kinases
