1st Midterm: Development of the Spine/Cervical Spine Flashcards
During the 2nd week the inner cell mass develops into a _________ _________ ________
Bilaminar Embryonic Disc
The cells of the upper BED layer are called ___________
Epiblast
From where or what part of the BED does the prechordal plate develop?
Hypoblast
The process by which the inner cell mass is converted into a trilaminar embryonic disc is called?
Gastrulation
From where does the intro-embryonic ectoderm come from? Epi or hypoblast?
Epiblast
The tip of the primitive streak is called?
The primitive knot
What develops from the tip of the primitive streak?
Notochordal process
The notochord is a cellular rod that develops between what two layers?
Ectoderm & Endoderm
The primitive axis of the embryo is formed from what structure?
Notochord
The somites form what part of the skeleton?
The axial skeleton
The notochord induces the development of what system of the body?
Central Nervous System
What is the process called when the central nervous system is formed from the notochord?
Neurulation
Neuroectoderm -> __________ ->___________->_________ ->__________
Neural Plate, Neural Groove, Neural Tube, Neural Crest Cells
Approx how many days is somatic development?
20-30
Each somite can differentiate in what 3 parts?
Sclerotome
Dermatome
Myotome
The ventormedial part of the somite is the ________
Sclerotome
The _________ is the dorsolateral part of the somite?
Dermatome
How many spinal nerves will innervate each somite?
1 spinal nerve
The Sclerotome is a condensation of what type of cells?
Mesenchymal
During the 4th week, mesenchymal cells derived from the Sclerotome migrate to what 3 areas?
Around the notochord to form the centrum of the vertebra
Around the Neural Tube to form the Neural Arch
In the body wall to form the ribs in the thoracic region.
Describe how many as well as the location of the chondrification centres during the 5&6th weeks of development.
Mesenchymal Verterbra:
2 centres in each Centrum
2 centres on each side of the Neural Arch
Ossification of typical vertebrae ends by ___ yoa
25
The halves of the vertebral arches usually fuse during the first how many years of life?
3-5
After puberty how many secondary ossification centres appear? Where are they located?
5
1 for the tip of the s.process
1 for each t.p
2 rim epiphyses one superior and one inferior rim of vertebral bodies.
The main features of this syndrome are short neck, low hairline, and restricted neck movements?
Klippel-Feil (Brevicollis) Syndrome
What is the severe type of Spina Bifida?
Cystica
Name the types of Spina Bifida Cystica
- Meningocele
- Meningomyelocele
- Myeloschisis
what type of SB has no nervous tissue in the cyst?
Meningocele
What type of SB has nervous tissue in the cyst and will impair function?
Meningomyelocele
Hemivertebra results from?
Failure of one of the two chondrification centres of the vertebral body to appear and subsequent failure of half of the vertebra to form.
This condition is the result of the failure of fusion of the Neural Folds and Neural Arch, because of faulty induction of underlying Notochord or because of Teratogenic Agents..
Rachischisis
Each Myotome divides into a small dorsal and large ventral division each called?
Small dorsal Epaxial/Epimere Divison
Large ventral Hypaxial/Hypomere Divison
The Myoblasts of the Epaxial Division form all what muscles of the spine?
Extensors
Myoblasts of the Hypaxial Division form what muscles?
Anterior muscles of the neck
Flexor muscles of the Spine
Quadratus Lumborum
Pelvic Diaphragm muscles
The derivatives of the Hypaxial/Hypomere division are innervated by branches from what Spinal Nerves?
The Ventral Primary Rami of Spinal Nerves
The Occiput consists of these 4 parts:
- Squamous portion
- Two lateral portions
- One basilar portion
What characteristic of the occiput is unique in newborns compared to adults?
All four parts are separate in the newborn with all four parts centred around the Foramen Magnum
What part of the occiput is the largest and expanded portion? Where is it located?
Squamous part - located posterior and above the f.magnum
An aka for Inion
External Occipital Protuberance
Where does the Nuchal Ligament attach?
EOP
What line is for the galea aponeurotic a attachment?
Highest (Supreme) Nuchal Line
What makes the supreme nuchal line unique?
Not always present in all bodies.
This structure extends inferiorly from the EOP to the F.Magnum?
External Occipital Crest
This line serves as an attachment for the Trapezius and SCM
Superior Nuchal Line
This line serves as an attachment for the sub occipital muscles?
Inferior Nuchal Line
What is the area above the highest nuchal line named? What is a unique feature of this structure?
Planum Occipitale - Smooth part of the occiput
What is the main difference between the Planum Occipitale and the Planum Nuchale?
Occipitale is smooth where the nuchale has ridges.
The cranial surface of the occiput is deeply _________ so that it can fit these two parts of the brain?
Concave
Cerebral and Cerebellar
The concavity of the cranial surface of the occiput is divided into how many fossae?
4