1st Flashcards
Normal pH
Co2
Hco2
pH 7.35-7.45
Co2 35-45
Hco2 - 22-26
Metabolic acidosis
Causes?
**Bicarb low ** - GI loss (diarrhea)
Acid high - increase in lactic acid (poor perfusion, carbon monoxide poisioning), DKA, toxin
Impaired renal exretion (not excreting acid)
alcoholism, starvation
S/S of Metabolic acidosis
Hyperkalemia = ECG monitoring, Tall Tented T waves
Kussmaul respiration (deep labored breathing)
Diarrhea, nausea
Fatique, confusion
What is compensation for metabolic acidosis
Nursing interventions - Monitor what labs
Lungs compensate by increasing resp/min to blow off co2
Monitor labs, serum lactic acid, replace fluids and electrolytes
Metabolic Alkalosis
Reasons
Gi loss (vomit, suction)
Ingesting too much bicarb (antiacids)
Diuretics, thiazides (excreting too much hydrogen in urine), hyperaldosteronism
Hypokalemia
S/S Metabolic alkalosis
Hypokalemia - Muscle cramps, weakness, twitching
Confusion, lethargy, dizzy
Compensatory - Hypoventilation
What is compensation for metabolic alkalosis
Nursing interventions
lung breath slower to hold on to Co2
ABGs, replace fluids/electrolytes, avoid suction
Respiratory acidosis
Causes
Acute vs Chronic
S/S
Compensation
Nursing intervention
Cause: hypoventilation/breathing slow
Acute - airway obstruction (choking, aspiration),chemical depression - overdose. Weak lungs - guillain barre, spinal cord injury
Chronic - obesity, COPD, emphysema
S/S hypoxia, confusion, lethargy, drowisness, headache
Compensation - secrete more H+, reabsorb bicarb, kidneys slow
Nursing interventions - Improve air way, HOB up, suction, O2, medications, poss IV push bi carb
Respiratory Alkalosis
Causes
S/S - late
Compensation
Nursing interventions
Causes: hyperventilation/breathing fast, releasing too much acid, panic attack, pneumonia, asthma exacerbation, pE, fever, high altitude, improper vent setting
**S/S ** lightheaded, dizzy, confusion, tachycardia, calcium imbalances (numbness & tingling), arrhythmias Late = seizure/coma
Compensation - reabsorb H+ , kidneys compensate slow
**Nursing interventions **- improve airway, 02 meds, encourage slow deep breathing. NOT paper bag.
Hyperphosphatemia
Causes & always assoc w/?
S/S
Interventions
Normal 2.7-4.5 mg/dl (4.5 mg/dl+)
Causes: From tumor lysis syndrome, decreased renal excretion, increased renal reabsorption (hyperparathyroidism), acidosis, hypoparathyroidism. always assoc with hypocalcemia
S/S - numbness, tingling, muscle spasms, tetany, larynogspasm, stridor, chvosteks and trousseau signs
**Nursing interventions **- Monitor serum levels, correct low calcium (calcium gluconate IV), monitor IV site, give phosphate binders (calcium carbonte) ALWAY DISSOLVE NEVER CHEW, 8 ounce water with meals. can cause constipation
Hyponatremia
Causes
S/S
Interventions
What precautions?
Replacing too quickly?
<135
Causes - too little sodium or too much water
* Sodium loss: Gi loss - vomit, NG suction, renal losses, diuretics, adrenal insufficiency, burns, fasting diets
* Excess water -Hypotonic IV fluids, polydipsia, cirrhosis, HF, SIADH
S/S - neurologic, cerebral edema, headache, nausea, vomiting, lethargy, confusion, seizures, coma.
Nursing interventions - monitor serum sodium, seizure precautions, replace sodium, fluid restriction, loop diuretics, don’t increase sodium too fast can lead to OSMOTIC DEMYELINATION SYNDROME = brain damage, monitor I &O
Metered Dose Inhaler
Deliver meds straight to lungs / avoid systemic side effects
Short acting beta agonists
Long acting
Inhaled corticosteroids
Primarily used for COPD
**SHake well for 3-5 sec, tilt head back slightly and exhale slowly for 3-5 sec. inhale and hold breath for 10 sec. Wait 1-2 mins before 2nd puff
Standard precautions
When do we use
How?
- All patients, all situations
- Hand hygiene (before/after contact
- Contact w/ blood, fluids, non-intact skin, mucous membranes, after removing gloves
Airborne precautions
When do we use it?
How?
Spread by small aerosolized particles
* Measles (Rubeola),
* Tuberculosis,
* Varicella
* Smallpox
* Covid
**MTV in ****S****mall **C**ountries
- Negative pressure room closed door
- N95
- Wear surgical mask when transported out of room
Droplet Precautions
When?
How?
spread by respiratory droplets
(Pertussis, flu, mumps, pneumoic plague, haemophilus influenza type B, neisseria meningitis) PIMPIN
- Private room
- Surgical mask
- Wear mask when transported out of room
Patients with what type of infection should be in isolated room first?
Airborne
Droplet
Contact
Airborne
What is abdominal Aortic aneurysm?
AAA
How diagnosed?
Risk factors?
S/S?
Trtmt?
Weakening in vessel wall creating a blood filled buldge
Diagnosed: Ultrasound, CT scan
Risk factor: Smoking, HTN, plaque, age, male
Pulsatile abdominal mass!!! Intense ab/back/flank pain, hypotension, tachycardia
TRTMT RBC, IV fluids, surgery, monitor I&O, peripheral pulses
Angina
Chronic?
Unstable?
Vasospastic?
Chest pain in response to MI or vasospasm
Chronic - fixed partial obstruction - occurs during exertion. STABLE and PREDICTABLE 02, beta blockers, Calcium blockers, nitro
Unstable/preinfarction - unpredictable. At rest or exertion. Sit upright, 02, 12 ECG, biomarkers, nitrate, morphine, coronary angiography
Variant/vasospastic - occurs at rest/sleep, triggered by smoking. May or may not be related to blockage, long acting nitrates, or Ca channel blockers
Alkalosis symptoms
*As the pH goes, so does my patient
What equiptment?
Except for potassium / hypokalemia & metabolic compensation breathing
Irritability, HTN, Tachypnea, tachycardia, Diarrhea, hyperreflexia, borborygmi (^bowel sounds), seizure
*Suction
Acidosis symptoms
*As the pH goes, so does my patient
expect what equiptment?
Except for potassium / hyperkalemia & metabolic compensation breathing
Hypotension, bradypnea (resp) / Kussmaul (metabolic), bradycardia, paralytic ilieus, constipation, hyporeflexia, flaccid, coma
*Resp arrest / ambu bag
What acid/base imbalance is Kussmaul resp
Metabolic acidosis
Aortic dissection
Type A
Type B
Risk
Diag
Trtment
Tear in aorta
Type A - affect heart & above. Sudden onset anterior chest pain. Tachycardic, diaphoretic. Fatal
Type B - heart & below. Ab/back pain. Reduced blood flow = Stroke, AKI, paralysis, cold legs/arms, MI
Risk: HTN, drug use, marfan syndrome
Diag: TEE, chest x ray, CT scan
*Trt: *reduce HR and BP. Labetalol or esmolol, upright position. Systolic between 100-120
Chronic venous insufficiency
Risk
S/S
Incompetent venous valvues = blood flows backwards and pools in leg
Risk: prolonged standing, DVT, obesity
S/S edema, red brown skin, Thick skin, ULCERS irregular shape above MEDIAL MALLEOLUS & painful in dependant position
if patietn has prolonged GI suction or vomit, what acid/base balance is it?
Metabolic alkalosis
For everything else that isnt lung or prolonged GI suction or vomit, what acid base imbalance?
Metabolic acidosis
Coronary Artery Disease (CAD)
Risk
S/S
Diag
Trtmt
Hardening of Coronary arteries due to plaque = impaired blood supply to heart
Risk: smoking, obesity, diet, stress. Family, sex, age, ethnicity. HTN, Hyperlipidemia
S/S asymptomatic until 50-70% is occulated then angina.
* Women - heartburn, epigastric pain
Diag - 12 lead, stress test, elevate lipid levels
Trtment - aspirin, clopideral, nitrates, statins, beta blockers, ACE, ca blocker, PCI, CABG
DVT
Causes (3)
S/S
Diag
Blood clot logged in deep veins (leg) blocked blood flow = inflammation
Causes: stasis (pooling), endothelial damage (surgery/trauma = more clotting factors), hypercoagulable state (preg)
S/S unilateral edema, pain, warmth, decreased sensation
Diag D-dimer, ultrasound
Trtmt anticoagulants, monitor for bleeding
MI
S/S
Atypical s/s
Diag
Trtmt
Unstable plaque ruptures and occuldes coronary artery = cell death
**S/S ** chest pain/ heavy pressure - radiating pain unreleaved by rest & nitro
Atypical S/S dizzy, tired, headache, GI syptpoms
Diag Changes in ST, cardiac enzymes (troponin, myoglobin, CK-MB) 4-6hours after MI
Trtmt Aspirin, Nitrates, Moprhine, 02, beta blockers, heparin
NSTEMI
Non ST elevated MI
Thrombus only partial occluding coronary artery / blood flow reduced
STEMI
ST seg elevation
Fully occlude / no blood flow
PCI
Percutaneous Coronary intervention
Perform within what time frame?
1st line treatment in MI
Perform within 90 mins
Thrombus retrieval, angioplasty, stent
CABG
Too large of blockage for a stent/balloon
Open heart / very invasive
Go around blockage from vein in leg
Peripheral Artery Disease (PAD)
S/S
Diag
Narrowing of arteroes due to atherosclerosis = decreased tissue perfusion
S/S* Intermittent claudication - ischemic pain during exertion relieved with rest*
Cool, dry, shiny skin, loss of hair, brittal nails, delayed pulse and cap refill. Tissue necrosis
Diag ankle brachial index. Pressures higher in Arm than leg in PAD
Septic Shock
Causes
S/S
Labs
Exaggerated immune response to microorganism causing vasodilation, leaky capillary, altered blood flow. Wide spread infection
Causes: gram - & + bacteria
S/S fever or hypothermia, tachycardia, persistent hypotension (leaky capillary), bounding pulses, resp distress, mental status changes, cold mottled skin
Labs Leukocytosis, positive blood cultures, increased blood glucose, lactic acid increase, coag alterations (DIC)
Signs of arterial insufficiency
Muscle pain
Decreased pulses
Hair loss
Cool, dry shiny skin
Gangrene
Thick brittle nails
Small circular deep ulcers
Signs of venous insufficiency
Varicose vein
Warm thick skin
Bronze brown color
Large irregular shaped superficial ulcer with drainage
edema
Diabetes insipidus
Central
Nephrogenic
S/S
Trtmt
Insufficient production of ADH by pit gland or lack of response to ADH
Central - Trauma or
Nephrogenic - resistance from kidneys from lithium, hypercalcemia, heredity
S/S polyuria, diluate and pale urine, freq urine, tachycardia, hypotension, dry mucous membranes, diminished peripheral pulses. Increased serum sodium, decreased urine specific gravity
Trtmt - central - desmopressin. Both hypotonic IV (.45% sodium chloride)
Diabetes Mellitus - TYPE 1
S/S
Need more insulin when?
Hypoglycemia?
Autoimmune destruction of panceatic beta cells
S/S - Thin. 3 P’s Polyuria, polydipsia, polyphagia, fruity breath, blurred vision, noturia, yeast infection.
*More insulin during illness, infection or stress
Hypoglycemia - under 70. Im glucagon if unconscious
DKA - process
S/S
Diagnosis
Trt
Lack of insulin = intracellular starvation = body uses fat for energy = high lvls of acidic keytones = kidneys increase excretion of excess glucose
* Diuresis - dehydration - hypovolemic shock
* 3P’s, nausea, fruity, kussmaul, lethargy, dry skin, hypotension, tachycardia, dizzy
Diag - blood glucose lvl, lvl serum/urine keytones, low serum pH, hyperkalemia
Trt - Fluid volume resus FIRST , then IV insulin. Then D5W to prevent glucose from getting too low
*pseudo hyperkalemia / monitor for rebound hypokalemia
Signs of hyperglycemia
Polyuria
Polydipsia
Nausea/Vomit
Fruity breath
Kussmaul respirations
Lethargy
Hypoparathyroidism
S/S
Monitor for
Trtmt
Parathyroids secrete PTH which affect calcium level
S/S decreased calcium, increased phos & decrease in PTH
Tingling, numbness, trousseau & chvostek sign, muscle cramp, pronlonged QT, Tetany, SEIZURES & precautions!
Monitor for dysrhythmias, high vit D (dark green & tofu), low phos diet
IV calcium gluconate
What does hormone PTH do
Cause bones to release calcium and increase renal absorption of calcium
PTH increases so does calcium. PTH decreases so does calcium
How to check Trousseau sign?
Check BP above Sys bp for 3 mins. Thumb and Wrist flex = positive
How to check Chvostek sign
Taping on facial nerve and patient spasm facial muscles
Acute Pancreatitis
Direct injury
Obstruction
S/S
Trtmt
Inflammation of pancreas
* Direct injury - alcohol, virus, meds (thiazide diuretics)
* obstruction - tumor, gallstones
S/S - severe ab pain after eating (epigastric/upper left ab/back), nausea/vomit, elevated lipase & amylase levels, CT shows inflammation
Trtmt - pain mgmt, IV fluids, antiemetics, NPO, monitor blood glucose and calcium lvls
Chronic pancreantitis
S/S
TRTMT
Repeated inflammation Can lead to fibrosis on pancreas
S/S ab pain, Malabsorption, fatty stools, weight loss, DM
TRTMT - small bland freq meals, give pancreatic enzymes w/ meals, supplement vit and minerals
SIADH
Causes
S/S
TRTMT
Excessive production of ADH = leads to excessive water retention
Causes:
* CNS disturbance (stroke, hemorrhage, trauma)
* Meds (pneumoia)
* Cancers
S/S Low urine output, Weight gain, HTN, Hyponatremia (confusion, seizures, coma), increased urine specific gravity
TRTMT - daily weight, I&O, neuro checks, Seziure precaution. Diuretics, vasopressin antagonists, monitor electrolytes