[1S] UNIT 1 Introduction to Pathology Flashcards

1
Q

DEFINITION OF TERMS

Etymology: Latin pathologia - “pathos” meaning “disease” and “logos” meaning “a treatise” - a treatise of disease

A

Pathology / Pathobiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

DEFINITION OF TERMS

Greek pathologikos (παθολογία): pathos - “suffering” (from PIE root *kwent(h) - “to suffer”) + -logia “study”

A

Pathology / Pathobiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

DEFINITION OF TERMS

It is a form of science and a branch of medicine that involves testing samples and diagnosing physical health problems from their evidence

A

Pathology / Pathobiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

DEFINITION OF TERMS

Study of the nature, causes, processes, development, consequences of disease and the modifications in cellular function and changes in cellular structure produced in any cell, organ, or part of the body by disease i.e. disease originates at the cellular level (Virchow)

A

Pathology / Pathobiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

DEFINITION OF TERMS

Arises from alterations in molecules (genes, proteins, etc.) that influences the survival and behavior of cells

A

Cellular disturbance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

DEFINITION OF TERMS

Understanding the cellular and molecular
abnormalities that give rise to disease

A

Foundation of Modern Pathology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

DEFINITION OF TERMS

Pathogenesis in Greek

A

πάθος pathos (“suffering”, “disease”) and γένεσις genesis (“creation”)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

DEFINITION OF TERMS

The development of a disease and the chain of events leading to that disease

A

Pathogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

DEFINITION OF TERMS

The biological mechanism (or mechanisms) that leads to a diseased state

A

Pathogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

DEFINITION OF TERMS

Pathology describes the abnormal condition, whereas pathophysiology seeks to explain the physiological processes because of which such condition develops and progresses

A

Pathophysiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

DEFINITION OF TERMS

Define the functional changes associated resulting from disease or injury

A

Pathophysiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

DEFINITION OF TERMS

● Malfunctioning of diseased cells
● Defines functional changes of tissues due to disease/injury

A

Pathophysiology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

DEFINITION OF TERMS

A physician who studies all aspects of disease with an emphasis on the nature, causes, and development of abnormal conditions, as well as the structural and functional changes that result from disease processes

A

Pathologist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

DEFINITION OF TERMS

A physician specialized in the interpretation and diagnosis of the gross, microscopic, and molecular cause by disease in the body

A

Pathologist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

DEFINITION OF TERMS

The laboratory specialist behind the front-line clinical team

A

Pathologist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

DEFINITION OF TERMS

The head of clinical laboratories supervising its different sections but if you are also certified as an anatomic pathologist, you can perform analyses of tissues and cells, and perform post-mortem examinations

A

Clinical Pathologist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

DEFINITION OF TERMS

Laboratory professional who performs diagnostic analysis on human blood, urine, and body fluids such as cerebral spinal fluid, peritoneal, pericardial, and synovial, as well as other specimens such as stool, sputum, etc.

A

Medical Technologist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

DEFINITION OF TERMS

A medical technologist who works under the histopathology section is called a _________

A

Histotechnician

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

DEFINITION OF TERMS

RMTs specialized in histopathologic techniques HT(ASCP)

A

Histotechnologist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

DEFINITION OF TERMS

Specialized personnel who belong in the histopathology laboratory

A

Histotechnologist

21
Q

DEFINITION OF TERMS

Doesn’t rotate to other sections of the laboratory

A

Histotechnologist

22
Q

DEFINITION OF TERMS

○ Influence of magic or supernatural
○ Derived from Greek, Onesimus, a revered orthodox saint who was believed to bring good luck from God

A

Anisim

23
Q

DEFINITION OF TERMS

○ Deficiency or excess body fluids
■ An excess in body fluids causes edema
○ Hippocrates: ‘Father of Medicine’

A

Humors

24
Q

DEFINITION OF TERMS

○ Study of cells (19th century)
○ Rudolf Virchow: ‘Father of Pathology’

A

Cellular Pathology

24
Q

DEFINITION OF TERMS

○ Postmortems & gross pathology (300 BC)
○ Van Leeuwenhoek: Microscope (17th century)

A

Morbid Anatomy

25
Q

DEFINITION OF TERMS

A
26
Q

DEFINITION OF TERMS

Examination of cells or tissues from a living organism and studied in order to diagnose disease or to confirm findings of normality. Tumors are routinely biopsied in order to determine whether they are benign or malignant.

A

Biopsy

27
Q

is a 1632 oil painting on canvas. Rembrandt van Rijn. Mauritshuis museum in The Hague, the Netherlands.

A

The Anatomy Lesson of Dr. Nicolaes Tulp

28
Q

DEFINITION OF TERMS

Partial removal of a small portion of tissues in the form of wedges, cylindrical pieces, cores, punch, or scrapings of the
suspected tissue or organ.

A

Incision Biopsy

29
Q

DEFINITION OF TERMS

Also called a wide local incision, involves surgical removal of a tumor and some normal tissue around it.

A

Excision Biopsy

30
Q

DEFINITION OF TERMS

The intention is to sample only a
representation portion of the lesion of interest.

A

Incision Biopsy

31
Q

DEFINITION OF TERMS

The amount of normal tissue taken (also called the surgical margin) depends on the
size, histologic type and thickness of the tumor.

A

Excision Biopsy

32
Q

DEFINITION OF TERMS

Greek αὐτοψία autopsia, “to see for oneself”, derived from αὐτός (autos, “oneself”) and ὄψις (opsis, “sight, view”), a
seeing for oneself : auto-, auto- + opsis, sight

A

Autopsy

33
Q

DEFINITION OF TERMS

Other terms for Autopsy

A

Post-Mortem Examination / Obduction / Necropsy / Autopsia Cadaverum

34
Q

DEFINITION OF TERMS

Surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death or to evaluate any disease or injury that may be present for research or educational purposes

A
35
Q

DEFINITION OF TERMS

Uses many methodical procedures to determine the etiology and pathogenesis of diseases, for epidemiologic purposes, for establishment of genetic causes, for family counsel, and for improvement of safety standards for the living.

A

Autopsy

35
Q

DEFINITION OF TERMS

Systematic examination of a cadaver for study or for determining the cause of death

A

Autopsy

36
Q

DEPARTMENT OF ANATOMIC PATHOLOGY PERSONNEL

How many
- Consultant Pathologists
- Resident Pathologists
- Chief MT
- Histotechnology Staff
- Clerk
- Lab Aide
- Mortician
- Rotating MTIs

A

Consultant Pathologists (20)
Resident Pathologists (11)
Chief Medical Technologist (1)
Histotechnology staff (5)
Clerk / Secretary (3)
Laboratory Aide (1)
Mortician (1)
Rotating Medical Technology Interns (6)*

36
Q

Total number of rotating Medical Technology Interns (6)

A

Surgical Pathology (1)
Cytology and RFS (1)
Immunohistochemistry (1)
Special staining procedures (1)
Autopsy (1)
Filing of blocks and slides (1)

37
Q
  • Gross specimen examination and cutting area
  • Tissue and slide processing, Microtomy / Staining area
  • Reception / Clerical area
A

Department of Anatomic Pathology

38
Q
  • Fine needle aspiration biopsy (FNAB) room
  • Frozen section and Cytopathology room
  • Fluorescence microscopy room (for renal and skin biopsies)
A

Department of Anatomic Pathology

39
Q
  • Proper receiving of specimens
  • Assisting in the gross cutting of specimens
  • Assist loading of the tissue processor
  • Microtomy: Block orientation, Rough cutting, soaking, and chilling, Ribboning, Floatation, Oven-drying
  • Staining
  • Coverslipping or slide mounting
  • Labelling
  • Reagent and Solution preparation
  • Filing of slides and blocks
A

Role of MTIs

39
Q
  • Immunohistochemistry
  • Tissue banking storage facility
  • Slide archival, chemical and storage rooms
A

Department of Anatomic Pathology

39
Q
  • Consultant / Residents / Histotechnologists working areas
  • Office of the Chairman and Chief Medical Technologist
  • Post-mortem examination (Autopsy) / Morgue
A

Department of Anatomic Pathology

40
Q

TRAINING PROGRAM FOR MTI SECTION OF HISTOPATH

How to properly receive a specimen?

A
  • Identification
  • Labeling
  • Logging / Recording
  • Fixation
41
Q

T/F: There are 2 histopathologic techniques in the MT profession.

A

F; 12

42
Q

T/F: Labels are added after dehydration.

A

F; Labels are added twice, a tentative label is added before Accessioning and the permanent label is added after Mounting.

42
Q

T/F: Incision biopsy is the complete removal of a suspected portion.

A

F

43
Q

T/F: Excision biopsy is the complete removal of a suspected portion

A

T